Phytochemical analysis and in vitro and in vivo evaluation of biological activities of artichoke (Cynara scolymus L.) floral stems: Towards the valorization of food by-products

Food Chemistry
Faiza MejriKarim Hosni

Abstract

Artichoke floral stems (AFS) food waste by-products were examined for their phytochemical constituents and their in vitro and in vivo biological activities. Although that the highest total phenol content and total flavonoid content were found in ethyl acetate extract, methanol extract possessed the strongest DPPH and ABTS radical scavenging activity, and showed the highest reducing ferric antioxidant power (FRAP). The anti-acetylcholinesterase activity was higher in butanol extract, whereas the ethyl acetate extract had the highest inhibitory effect on heat-induced protein denaturation. In alloxan-induced diabetic mice, the AFS methanol extract (AFSE) rich in caffeoylquinic acids and flavones reduced blood glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, creatinine, and improved liver, and renal antioxidative status. Administration of AFSE to diabetic mice reduced total cholesterol, triglycerides, LDL-cholesterol, and the atherogenic index of plasma (AIP) suggesting its hypolipidemic action. Overall, AFS could be considered as attractive source of health-promoting ingredients.

References

Jan 1, 1990·Methods in Enzymology·H H Draper, M Hadley
Jan 1, 1984·Methods in Enzymology·L Flohé, W A Günzler
Jan 1, 1984·Methods in Enzymology·H Aebi
Jun 25, 1999·Free Radical Biology & Medicine·R ReC Rice-Evans
May 2, 2003·Journal of Agricultural and Food Chemistry·Michael N CliffordNikolai Kuhnert
Nov 26, 2004·Journal of Agricultural and Food Chemistry·Xianfeng ZhuRaymond Lo
May 12, 2005·Journal of Agricultural and Food Chemistry·Michael N CliffordNikolai Kuhnert
Jun 21, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Kasiappan RaviSorimuthu Subramanian
Dec 11, 2008·Basic & Clinical Pharmacology & Toxicology·Kunga Mohan RamkumarPalanisamy Rajaguru
Dec 4, 2009·The Journal of Nutritional Biochemistry·Li DingXiaoli Chen
Mar 24, 2010·Phytotherapy Research : PTR·Amélia P RauterJorge Justino
Jan 10, 2012·Biological & Pharmaceutical Bulletin·Kwang Sik SuhSuk Chon
May 12, 2017·Food & Function·Spyridon A PetropoulosIsabel C F R Ferreira
Oct 10, 2018·Frontiers in Nutrition·Hannah CoryJosiemer Mattei
Oct 12, 2018·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Heitor Oliveira SantosJoão Felipe Mota

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Jan 23, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ilaria ChiocchioFerruccio Poli

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