Phytochemical, therapeutic, and ethnopharmacological overview for a traditionally important herb: Boerhavia diffusa Linn

BioMed Research International
Shikha MishraSanjay Madhukar Jachak


Boerhavia diffusa (BD) is a plant of rasayana category as per ayurvedic claims. It is reported to possess antiaging, disease prevention, and life strengthening activities which hold enormous influence in disease burden and affordability/availability of healthcare in the world. Objective. This paper has been compiled to comment on the studies reported for BD to highlight its chemical and therapeutic potential along with its ethnopharmacological considerations. In the present paper, a detailed account of chemical constituents and pharmacological activities has been presented. All the findings were correlated with modern pharmacological activities to appraise the value of BD. Chemical analysis of BD gives a wide variety of chemical constituents, namely, rotenoids, flavonoids, xanthones, purine nucleoside, lignans, and steroids. Various ethnopharmacological reports emphasize its role in disorders of reproductive system, gastrointestinal system, respiratory system, urinary system, hepatic system/jaundice, cardiovascular system, and cancer. The studies on the therapeutic activities of BD range from studies on crude extracts to isolated compounds; however some of the studies require sophistication and validated results. BD is a plant ...Continue Reading


Dec 26, 1992·Annals of the New York Academy of Sciences·D Harman
Mar 1, 1991·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·M Barthwal, K Srivastava
Mar 1, 1991·Journal of Ethnopharmacology·B K ChandanK K Anand
Jun 1, 1990·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·M Barthwal, K Srivastava
May 1, 1993·Journal of Ethnopharmacology·D K OlukoyaT Odugbemi
Mar 1, 1997·Journal of Ethnopharmacology·A K RawatU Shome
Aug 28, 1999·Journal of Ethnopharmacology·A A MungantiwarK B Sainis
Jul 25, 2000·Journal of Ethnopharmacology·C A Hiruma-LimaA R Souza Brito
May 16, 2002·Experimental and Molecular Pathology·S MehrotraR C Srimal
Aug 22, 2002·International Immunopharmacology·S MehrotraV K Singh
Jan 11, 2005·Current Medicinal Chemistry·Mária Báthori, Zita Pongrácz
Jan 27, 2005·Journal of Medicinal Food·L Pari, M Amarnath Satheesh
Feb 3, 2005·International Immunopharmacology·Rahul PandeySita Naik
May 17, 2005·Journal of Ethnopharmacology·R GovindarajanP Pushpangadan
Oct 29, 2005·Planta medica·Francesca BorrelliOrazio Taglialatela-Scafati
Nov 8, 2005·Journal of Ethnobiology and Ethnomedicine·Luiz Rodrigo Saldanha GazzaneoUlysses Paulino de Albuquerque
Mar 7, 2006·International Journal of Pharmaceutics·Sang-Chul ShinXiuguo Li
Jun 24, 2006·Journal of Natural Products·Francesca BorrelliOrazio Taglialatela-Scafati
Nov 17, 2006·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·M De MartinisL Ginaldi
Mar 8, 2007·Journal of Medicinal Chemistry·Abdelhakim Ahmed-BelkacemAttilio Di Pietro
Mar 1, 1982·Planta medica·O P SuriC K Atal
Jul 4, 2007·Journal of Ethnopharmacology·N SavithrammaK N Rao
Aug 16, 2008·Annals of African Medicine·M O A Samaila
Sep 3, 2009·Journal of Ethnopharmacology·Sreekumar Sreeja, Sreeharshan Sreeja
Oct 7, 2009·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Rainer CermakPeter Langguth
Dec 2, 2009·Evidence-based Complementary and Alternative Medicine : ECAM·Mandeep Kaur, Rajesh Kumar Goel
Jun 18, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M Tolulope OlaleyeAfolabi A Akindahunsi
Aug 27, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Rakhi SrivastavaMadhu Chopra
Aug 7, 2013·Journal of Natural Products·Khemraj BairwaSanjay Madhukar Jachak
Mar 29, 2014·Phytochemical Analysis : PCA·Khemraj BairwaSanjay Madhukar Jachak


Mar 25, 2017·FEBS Letters·Mihika BoseAnjali A Karande
Sep 18, 2018·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Jennifer Joan RyanRyan Bradley
Feb 21, 2020·BioMed Research International·Mohammad Arif Ashraf
Oct 13, 2017·The Journal of Pharmacy and Pharmacology·Ewura Seidu YahayaVanessa Steenkamp
Jan 25, 2021·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Kanika KhannaParvaiz Ahmad
Mar 6, 2021·Frontiers in Genetics·Sreyashi MajumdarSudipto Saha
Apr 12, 2020·The Science of the Total Environment·Balachandar VellingiriMohana Devi Subramaniam
May 12, 2021·Journal of Complementary & Integrative Medicine·Aswathi Rajan Vaprath KuniyilJames Chacko

Methods Mentioned

column chromatography

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.