Phytochemistry and Pharmacology of Phyllanthus niruri L.: A Review

Phytotherapy Research : PTR
Navneet KaurGeetika Sirhindi

Abstract

Phyllanthus niruri, a typical member of family Euphorbiaceae, is a small annual herb found throughout the tropical and subtropical regions of both hemispheres. The genus Phyllanthus has been used in traditional medicine for its wide range of pharmacological activities like antimicrobial, antioxidant, anticancer, antiinflammatory, antiplasmodial, antiviral, diuretic and hepatoprotective. This review summarizes the information about morphological, biochemical, ethanobotanical, pharmacological, biological and toxicological activities with special emphasis on mechanism of anticancer activity of P. niruri. Gaps in previous studies such as taxonomic inconsistency of P. niruri, novel phytochemicals and their therapeutic properties, especially mechanisms of anticancerous activity and market products available, have been looked into and addressed. Scientific information related to 83 phytochemicals (including many novel compounds detected recently by the authors) has been provided in a very comprehensive manner. Copyright © 2017 John Wiley & Sons, Ltd.

References

Dec 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M HoffmanI Yust
May 1, 1987·Medicine·R SlimanD M Shlaes
Jan 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·P S VenkateswaranB S Blumberg
Sep 1, 1985·Journal of Ethnopharmacology·K V SyamasundarH Hikino
Feb 1, 1968·Archives of Internal Medicine·W H Dodson
Mar 1, 1983·Reviews of Infectious Diseases·G P BodeyL Jadeja
Nov 1, 1984·Journal of Natural Products·D R Gupta, B Ahmed
May 8, 1981·Mycopathologia·M L EscheteA Oberle
Nov 1, 1981·Australian Veterinary Journal·J A Gibson, L E Eaves
Jan 1, 1996·Psychoneuroendocrinology·S Retana-MarquezJ Velazquez-Moctezuma
Feb 1, 1996·Journal of Natural Products·J Qian-CutroneK F Kadow
Feb 12, 1998·Journal of Clinical Microbiology·N OkhraviS Lightman
Mar 25, 2000·The American Journal of Clinical Nutrition·V M HegartyK T Khaw
Jul 4, 2001·Trends in Microbiology·R A Calderone, W A Fonzi
May 17, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Allan R Tunkel, Kent A Sepkowitz
May 22, 2002·Journal of Ethnopharmacology·N V RajeshkumarRamadasan Kuttan
Aug 10, 2002·Journal of Ethnopharmacology·A K KhannaR Chander
Feb 5, 2003·The American Journal of Medicine·Penny M Kris-EthertonTerry D Etherton
May 29, 2003·Current Drug Metabolism·Yin-Yin Ow, Ieva Stupans
Dec 18, 2003·Journal of the European Academy of Dermatology and Venereology : JEADV·C Pina-VazJ Martinez-de-Oliveira
Jun 10, 2004·Journal of Agricultural and Food Chemistry·Alicia MarínMaría I Gil
Jul 6, 2004·Journal of Ethnopharmacology·Tomonori UnnoTakami Kakuda
Jul 13, 2004·Bioorganic & Medicinal Chemistry·Kadali S SagarShoei-Sheng Lee
Dec 17, 2004·Nature·Jon Clardy, Christopher Walsh
Apr 23, 2005·Journal of Natural Products·Subeki SubekiTeruhiko Yoshihara
Jul 8, 2005·Lymphatic Research and Biology·Nicholas Farinola, Neil Piller

❮ Previous
Next ❯

Citations

Mar 9, 2019·Anti-cancer Agents in Medicinal Chemistry·Fanghua QiuFeng Qiu
Jun 23, 2018·Journal of Basic and Clinical Physiology and Pharmacology·Varinder SinghRicha Shri
Oct 18, 2018·Frontiers in Pharmacology·Madamanchi Geethangili, Shih-Torng Ding
Apr 24, 2018·Environmental Monitoring and Assessment·Vanessa Santana Vieira SantosBoscolli Barbosa Pereira
Oct 13, 2018·Scientific Reports·Elenilson G Alves FilhoGuilherme J Zocolo
May 21, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Juliano G HaddadChaker El Kalamouni
Jan 24, 2021·Journal of Ethnopharmacology·Maciel da Costa AlvesJuliana Késsia Barbosa Soares
Feb 13, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·José Assis Gomes de BritoFernando Cotinguiba

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.