PMID: 1203845Jul 1, 1975Paper

Phytohemagglutinin-induced lymphocyte transformation in newly presenting patients with primary carcinoma of the lung

Cancer
E W BarnesN W Horne

Abstract

The transformation of peripheral blood lymphocytes in response to PHA was studied in 37 newly presenting patients who were subsequently proven to have carcinoma of the lung. When compared with healthy age- and sex-matched normal controls, no differences were noted in the thymidine uptake of the unstimulated lymphocytes in culture or in the response to any of the three dose levels of PHA used. Neither the extent of the spread of the carcinoma nor the type of its histology showed any correlation with the PHA response, but the PHA response was significantly depressed within 14 days of death in 7 patients. No evidence for serum inhibitory factors was found.

References

Jan 9, 1971·Lancet·S K ParkW S Blakemore
Feb 21, 1973·Nature: New Biology·B Phillips, I M Roitt
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Feb 12, 1972·British Medical Journal·C Hagen, A Froland
Jul 8, 1967·Nature·A V PisciottaB Walsh

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Citations

Jan 1, 1983·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·H KatoM Kondo
Mar 16, 2000·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·H NakamuraH Kato
Aug 18, 1977·The New England Journal of Medicine·B PaigenN T Hayner
Feb 1, 1978·Journal of Clinical Pathology·G M Gyte, S M Watkins
Oct 1, 1976·Thorax·D A Evans
Feb 1, 1977·Thorax·H L RobertsD A Price Evans
Jan 1, 1978·Acta Radiologica: Oncology, Radiation, Physics, Biology·E Nordman, A Toivanen
Oct 15, 1978·International Journal of Cancer. Journal International Du Cancer·E WardM B Havens
Mar 15, 1979·International Journal of Cancer. Journal International Du Cancer·R PrasadJ Tsuang
Jan 15, 1980·International Journal of Cancer. Journal International Du Cancer·G B CannonN P Lang
Oct 1, 1979·The Journal of Urology·M Menon, S S Stefani

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