Phytopharmacological evaluation of ethanol extract of Sida cordifolia L. roots

Asian Pacific Journal of Tropical Biomedicine
Mohammad Abdul Motalib MominTalha Bin Emran

Abstract

To investigate the phytochemical screening (group determination) and selected pharmacological activities (antioxidant, antimicrobial and analgesic activity) of the plant Sida cordifolia Linn (S. cordifolia). Eighty percent concentrated ethanol extract of the roots was used. To identify the chemical constituents of plant extract standard procedures were followed. In phytochemical screening the crude extract was tested for the presence of different chemical groups like reducing sugar, tannins, saponins, steroids, flavonoids, gums, alkaloids and glycosides. The antioxidant property of ethanolic extract of S. cordifolia was assessed by DPPH free radical scavenging activity. Analgesic activity of the extract was tested using the model of acetic acid induced writhing in mice. Diclofenac sodium is used as reference standard drug for the analgesic activity test. Antibacterial activity of plant extract was carried out using disc diffusion method with five pathogenic bacteria comparison with kanamycin as a standard. Phytochemical analysis of the ethanolic extract of the roots of S. cordifolia indicated the presence of reducing sugar, alkaloids, steroids and saponins. In DPPH scavenging assay the IC50 value was found to be 50 μg/mL which ...Continue Reading

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Citations

Aug 9, 2016·BMC Complementary and Alternative Medicine·Maqsood A SiddiquiMuhammad Iqbal Choudhary
Aug 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Israt JahanJesus Simal-Gandara
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May 1, 2021·Plants·Md Masudur RahmanJesus Simal-Gandara

Related Concepts

Ethanol
Antinociceptive Agents
Antioxidant Effect
Plant Extracts
Plant bulb
Vinegar
Sida <angiosperm>
Acetic Acid
Antibiotics
Antioxidants

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