Piezoresistivity in single DNA molecules

Nature Communications
Christopher BruotNongjian Tao

Abstract

Piezoresistivity is a fundamental property of materials that has found many device applications. Here we report piezoresistivity in double helical DNA molecules. By studying the dependence of molecular conductance and piezoresistivity of single DNA molecules with different sequences and lengths, and performing molecular orbital calculations, we show that the piezoresistivity of DNA is caused by force-induced changes in the π-π electronic coupling between neighbouring bases, and in the activation energy of hole hopping. We describe the results in terms of thermal activated hopping model together with the ladder-based mechanical model for DNA proposed by de Gennes.

References

Feb 9, 1996·Science·P CluzelF Caron
Jul 1, 1997·Chemistry & Biology·A NoyC M Lieber
Mar 25, 1996·Physical Review Letters·G RubioS Vieira
Feb 25, 2000·Mutation Research·S R RajskiJ K Barton
Jul 14, 2000·Nature·F D LewisM R Wasielewski
Dec 25, 2003·Journal of the American Chemical Society·Bingqian XuNongjian J Tao
Aug 10, 2005·Proceedings of the National Academy of Sciences of the United States of America·Hezy CohenDanny Porath
Dec 14, 2005·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Harm van ZalingeRichard J Nichols
Dec 17, 2005·Nucleic Acids Research·Stefano Piana
May 11, 2006·Nano Letters·Rahul ChhabraHao Yan
Jul 13, 2006·Nano Letters·Alejandra V GaribottiNadrian C Seeman
Nov 27, 2009·Accounts of Chemical Research·Sriram KanvahUzi Landman
Jan 22, 2010·Nanotechnology·Thi-Huong NguyenEui-Sung Yoon
Jan 1, 2009·Proceedings of the IEEE·A Alvin BarlianBeth L Pruitt
Sep 25, 2010·Journal of the American Chemical Society·Sarah M Mickley ConronFrederick D Lewis
Feb 22, 2011·Nature Nanotechnology·Ismael Diez-PerezNongjian Tao
Dec 6, 2011·Nature Nanotechnology·Christopher BruotNongjian Tao
Nov 22, 2012·Journal of the American Chemical Society·Jeffrey S MeisnerColin Nuckolls
Nov 5, 2013·The Journal of Chemical Physics·S NathS Kumar
Dec 23, 2014·ACS Nano·Christopher BruotNongjian Tao
Feb 17, 2015·Nature Materials·Habid Rascón-RamosJoshua Hihath
Feb 24, 2015·Nature Chemistry·Limin XiangNongjian Tao

❮ Previous
Next ❯

Citations

Oct 20, 2015·Journal of the American Chemical Society·Christopher BruotNongjian Tao
Jan 26, 2017·Topics in Current Chemistry·Kun Wang, Bingqian Xu
Feb 22, 2017·Nature Communications·Limin XiangNongjian Tao
Jan 18, 2018·Journal of Functional Biomaterials·Kun Wang
Oct 17, 2019·Physical Chemistry Chemical Physics : PCCP·Saientan Bag, Prabal K Maiti
Aug 27, 2019·Nanoscale Research Letters·Thomas P Collier, Mikhail E Portnoi
Aug 23, 2018·Nano Letters·Davide StefaniHerre S J van der Zant
Aug 21, 2021·Biosensors & Bioelectronics·Yuan WangQuan Qing

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis
force spectroscopy

Software Mentioned

Origin
Labview

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.