Pig lenses in a lens stretcher: implications for presbyopia treatment

Optometry and Vision Science : Official Publication of the American Academy of Optometry
Robert KammelStefan Nolte

Abstract

To investigate porcine lenses in a lens stretcher with regard to presbyopia corrective procedures. A lens stretching device was designed, which allows to simultaneously determine all relevant geometrical and optical parameters at each stretch position. The setup was used to compare the optical and geometrical lens properties of young slaughter pigs (n = 5) with older sows (n = 7). The change of optical power with stretching is about five times larger for young porcine lenses than for sows. For young pigs, the gradient index profile of the crystalline lens significantly contributes to the induced accommodation amplitude. We have shown that sow lenses are a suitable model for in vitro experiments on possible treatments for presbyopia. The rapid decrease in the induced accommodation amplitude with age may be explained by a reduced change of all geometrical lens parameters, which in turn leads to a smaller contribution of the gradient index profile to accommodation.

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Citations

Oct 10, 2013·Lasers in Surgery and Medicine·Marina MerkerStefan Nolte
Sep 24, 2019·Investigative Ophthalmology & Visual Science·Bharat KumarMatthew A Reilly
Feb 24, 2015·Experimental Eye Research·Lisanne M NibourgSteven A Koopmans

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