Pilomatrical neoplasms in children and young adults

The American Journal of Dermatopathology
A J MarrogiL P Dehner


Pilomatrixoma, a neoplasm of hair germ matrix origin, is one of the most common cutaneous appendage tumors in patients 20 years of age or younger. Our review of cutaneous adnexal tumors in the first 2 decades of life showed that pilomatric lesions accounted for approximately 75% of cases. We examined 76 tumors from 69 patients between the ages of 8 months and 19 years (average age, 8 years). The female-to-male ratio was 3:1. We noted a predilection for the head and neck region, as has also been reported by other investigators. Sixty-nine tumors were examples of typical or classic pilomatrixoma; four of them showed the unusual histologic feature of transepidermal elimination or perforation. None of the tumors in the typical category recurred during a follow-up period that averaged 8.7 years. Seven of the lesions with atypical histologic features were examples of aggressive pilomatrixoma (three cases) and pilomatrical carcinoma (four cases). The average age of these seven patients was similar to that of the overall group. The pilomatrical carcinomas were characterized by invasive nests of tumor cells with irregular borders, large vesicular nuclei, prominent nucleoli, multiple mitotic figures, and focal necrosis. A desmoplastic st...Continue Reading


Mar 20, 2009·Skeletal Radiology·Hye Jung ChooDong Wook Kim
Jul 31, 2009·Cancer Causes & Control : CCC·Christine M MuellerMark H Greene
Aug 16, 2000·Pediatric Clinics of North America·A J Wyatt, R C Hansen
Mar 1, 1996·American Journal of Otolaryngology·M RotenbergD Brasnu
Aug 17, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R M BremnesE A Jacobsen
Aug 1, 1996·The American Journal of Dermatopathology·S KadduH Kerl
Aug 14, 1999·The American Journal of Dermatopathology·J A CarlsonM C Mihm
Jan 22, 2002·The American Journal of Dermatopathology·D HardissonF Contreras
Sep 1, 1996·Plastic and Reconstructive Surgery·G AslanA Terzioğlu
Dec 10, 2003·Plastic and Reconstructive Surgery·Ashkan PirouzmaneshJohn G Meara
May 22, 2010·The American Journal of Dermatopathology·Elzbieta A SlodkowskaJ Andrew Carlson
Sep 15, 2011·The American Journal of Dermatopathology·Ji-Won ByunGwang-Seong Choi
May 1, 1994·International Journal of Dermatology·A ItamiA Kukita
Oct 1, 1994·International Journal of Dermatology·S KadduS Hödl
Nov 19, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jeffrey M MelanconShang I Brian Jiang
Dec 1, 1995·Pediatric Dermatology·R M PujolJ M de Moragas
May 23, 2012·Head & Neck Oncology·Tahwinder UpileHani Radhi
Apr 20, 2014·Journal of Clinical Imaging Science·Huseyin ToprakSalih Ozgocmen
Mar 22, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Francesca D BeamanJames H Keeling
Jun 1, 2014·Archives of Pathology & Laboratory Medicine·Stefan Kraft, Scott R Granter
Mar 14, 2002·The Journal of Dermatology·Yoshihide HondaYasumoto Tokuda
Apr 1, 1997·Journal of Cutaneous Pathology·S KadduH Kerl
Oct 22, 2008·Survey of Ophthalmology·Jaime LevyJacob Pe'er
Apr 27, 2007·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Atsuko SakaiAkiteru Hayashi
Mar 27, 2012·Journal of Cutaneous Pathology·Sarah KarramIbrahim Khalifeh
Apr 21, 2012·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Silvina SímulaNorberto Sanjuan
Apr 1, 1995·Pathology·D MonchyD Dubourdieu
Dec 3, 2014·Acta otorrinolaringológica española·Mainak DuttaShaswati Sengupta
Apr 18, 2014·Journal of the American Academy of Dermatology·Jennifer L HerrmannMichael B Morgan
Nov 22, 2001·Clinical Oncology : a Journal of the Royal College of Radiologists·N G Mikhaeel, M F Spittle
Dec 18, 2014·Archives of Dermatological Research·Rocco CappellessoAmbrogio Fassina
Aug 1, 1997·The Journal of Dermatology·K AraiK Iwasaki
Jul 31, 2013·Journal of Pediatric Surgery·Saif F HassanMary L Brandt
Oct 11, 2016·Seminars in Diagnostic Pathology·Alejandro A Gru, M D Horacio Maluf
Feb 1, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·A Neil CrowsonMartin C Mihm
Apr 20, 2001·The Australasian Journal of Dermatology·M R KhammashA Abalkhail
Oct 1, 2013·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Richard SalzmanTomas Tichy
Feb 1, 1996·The British Journal of Dermatology·T A McCullochD W Cotton
Aug 30, 2008·Pediatric Hematology and Oncology·Emre CecenFaik Sarialioglu
May 8, 2014·Ophthalmic Plastic and Reconstructive Surgery·Ofira ZlotoMordechai Rosner
Apr 30, 2002·The American Journal of Dermatopathology·Maria Victoria De Gálvez-ArandaAlfredo Matilla-Vicente
Feb 27, 2004·Journal of Cutaneous Pathology·Virginia G Hubbard, Sean J Whittaker
Jul 9, 2004·Clinical Orthopaedics and Related Research·R Scott MeyerMichael J Botte
Dec 21, 2004·Journal of Cutaneous Pathology·Alexander J F LazarPhillip H McKee
Sep 23, 2021·Ear, Nose, & Throat Journal·Adelaide ZhaoGlenn Isaacson

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved