PMID: 11801770Jan 22, 2002Paper

Pilomatrix carcinoma: a clinicopathologic study of six cases and review of the literature

The American Journal of Dermatopathology
D HardissonF Contreras

Abstract

Pilomatrix carcinoma, the malignant variant of pilomatrixoma, is a rare entity. The authors report on six patients with pilomatrix carcinoma and review the pertinent literature. The lesions showed a predilection for elderly individuals (mean age, 61 years) with a male:female ratio of 5:1, and they presented as dermal or subcutaneous tumors located on the head and neck (5 neoplasms) and chest (1 neoplasm). Tumors varied in size from 0.6 cm to 2.5 cm (mean, 1.78 cm). None of the lesions recurred after wide local excision. On scanning magnification, all tumors showed the architectural features of a malignant neoplasm (asymmetry and poor circumscription, presence of several markedly sized and variably shaped basaloid aggregations, and ulceration). The tumors were composed of pleomorphic basaloid cells with prominent nucleoli and frequent atypical mitoses accompanied by central areas with keratotic material, shadow cells, and foci of necrosis. The tumor nests were surrounded by a desmoplastic stroma and infiltrated the adjacent tissues. Vascular or perineural infiltration was not observed. In one case, the basaloid cells contained abundant melanin pigment in their cytoplasms. Pilomatrix carcinoma is a neoplasm of low-grade malignanc...Continue Reading

References

Dec 1, 1976·Archives of Otolaryngology·C T SasakiR Enriques
Jan 1, 1976·Archives of Surgery·D RothmanA Baldi
Jun 1, 1992·Journal of Cutaneous Pathology·J B SloanC Jaworsky
Aug 1, 1992·The American Journal of Dermatopathology·P AmbrojoE Sánchez Yus
Apr 1, 1992·The American Journal of Dermatopathology·A J MarrogiL P Dehner
Nov 1, 1990·Journal of the American Academy of Dermatology·L BridgerS Harawi
Aug 1, 1990·Plastic and Reconstructive Surgery·M E KrugmanE Strout
May 1, 1990·The Journal of Dermatology·H MiyaharaH Kohda
Jan 1, 1989·Neuroradiology·F CampoyF Campoy
Dec 1, 1988·The American Journal of Dermatopathology·F G AloiM Pippione
Mar 1, 1988·Journal of Surgical Oncology·W C LineaweaverP L Leboit
Jan 1, 1986·British Journal of Plastic Surgery·D V NieldM H Ali
Aug 1, 1987·Journal of the American Academy of Dermatology·D E GreenM R Fowler
Oct 1, 1987·The American Journal of Dermatopathology·P E LeBoitS H Choy
Oct 1, 1986·Journal of Surgical Oncology·K T Chen, D R Taylor
Apr 1, 1974·The Laryngoscope·A S KrausenB R Mays
Jan 1, 1984·Acta Radiologica. Oncology·A J VeliathD Gomathinayagam
Feb 1, 1984·The American Journal of Dermatopathology·J D van der Walt, B Rohlova
Jun 1, 1984·Archives of Dermatology·M G WoodH Beerman
Feb 1, 1980·Journal of Cutaneous Pathology·D WeedonJ Mayze
Oct 1, 1993·Histopathology·D G O'DonovanD E Markham
May 1, 1994·Histopathology·P CrossJ Coyne
Apr 15, 1993·Cancer·P SauJ H Graham
Feb 1, 1996·The British Journal of Dermatology·T A McCullochD W Cotton
Apr 1, 1997·Journal of Cutaneous Pathology·S KadduH Kerl
Aug 1, 1997·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P VicoR Deraemaecker
Jul 29, 1998·International Journal of Dermatology·L WaxteinL Dominguez-Soto
Apr 28, 1999·American Journal of Ophthalmology·M T CahillS M Kennedy
Aug 14, 1999·The American Journal of Dermatopathology·J A CarlsonM C Mihm
Aug 17, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R M BremnesE A Jacobsen
Apr 1, 1961·Archives of Dermatology·R FORBIS, E B HELWIG

❮ Previous
Next ❯

Citations

Dec 27, 2006·Pathology Oncology Research : POR·Takeshi Kondo, Yoshio Tanaka
Oct 3, 2002·The American Journal of Dermatopathology·Michal ZamecnikPetr Mukensnabl
Nov 25, 2003·The American Journal of Dermatopathology·Carlos MonteagudoCarmen Carda
Sep 25, 2007·The American Journal of Dermatopathology·Rachele Del SordoAngelo Sidoni
Jun 8, 2010·The American Journal of Dermatopathology·Daniel LalichGarth Fraga
Sep 15, 2011·The American Journal of Dermatopathology·Ji-Won ByunGwang-Seong Choi
Dec 12, 2012·The American Journal of Dermatopathology·Kristine M Cornejo, April Deng
Nov 19, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jeffrey M MelanconShang I Brian Jiang
Jun 1, 2014·Archives of Pathology & Laboratory Medicine·Stefan Kraft, Scott R Granter
Jul 28, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·David Sable, Stephen N Snow
Jul 26, 2005·European Journal of Pediatrics·Bruno CiglianoMaria Angelica Fabbro
Feb 26, 2005·The British Journal of Radiology·T NiwaT Inoue
Apr 1, 2013·Journal of Medical Ultrasonics·Suk Jung Kim
Mar 5, 2016·Gynecologic Oncology Reports·Mihae SongDarlene Gibbon
Aug 13, 2015·Journal of Cutaneous Pathology·Sui Wing Winney Chu, Asok Biswas
Jul 3, 2010·The British Journal of Oral & Maxillofacial Surgery·N O'ConnorM Ethunandan
May 4, 2010·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·N TawfiqA Abdelouafi
Sep 25, 2009·Actas dermo-sifiliográficas·R Jiménez-PuyaJ C Moreno-Giménez
Nov 26, 2008·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·L AutelitanoG Colletti
Mar 12, 2016·Gynécologie, obstétrique & fertilité·M KäppeliP Judlin
Sep 22, 2007·The British Journal of Oral & Maxillofacial Surgery·Nicholas ZachariadesHelen Machera
Apr 27, 2007·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Atsuko SakaiAkiteru Hayashi
Dec 21, 2004·Journal of Cutaneous Pathology·Alexander J F LazarPhillip H McKee
Feb 11, 2005·Journal of Cutaneous Pathology·Henry D HaskellAlexander J F Lazar
Jul 23, 2013·International Journal of Dermatology·Mhair S DekmezianJaime A Tschen
Dec 11, 2013·Journal of Cutaneous Pathology·Flavia FedelesLeslie Robinson-Bostom
Mar 29, 2014·Journal of Cutaneous Pathology·Maxime BattistellaBernard Cribier
Apr 18, 2014·Journal of the American Academy of Dermatology·Jennifer L HerrmannMichael B Morgan
Jul 31, 2013·Journal of Pediatric Surgery·Saif F HassanMary L Brandt
Apr 24, 2012·Journal of Comparative Pathology·E O da SilvaA P F R L Bracarense
Jun 16, 2016·The Australasian Journal of Dermatology·Robert L GrohsBenjamin A Wood
Sep 2, 2016·Journal of the American Veterinary Medical Association·Rebecca A Kohnken, Christopher Premanandan
Sep 28, 2016·The American Journal of Dermatopathology·Mario N OteroSamuel D Morales
Apr 4, 2017·The American Journal of Surgical Pathology·Liubov KyrpychovaDmitry V Kazakov
Oct 13, 2006·Annales de chirurgie plastique et esthétique·B PulvermackerM Mitrofanoff
Oct 21, 2016·The American Journal of Dermatopathology·Chao JiYing Guo
Jan 26, 2018·Journal of Cutaneous Pathology·Katherine Tumminello, Gregory A Hosler
Dec 9, 2010·Rare Tumors·Alejandro Peralta SolerJames L Burchette
Jan 8, 2019·Archives of Craniofacial Surgery·Yang Seok KimJi Min Kim
Dec 26, 2018·Journal of Cutaneous Pathology·Daisuke Mori
Feb 21, 2019·Journal of Cutaneous Pathology·Larisa LehmerSebastien de Feraudy
Jan 13, 2012·Journal of Pediatric Orthopedics. Part B·Bradley John KinneyElizabeth E Frauenhoffer
Apr 30, 2017·Molecular and Clinical Oncology·Marios PapadakisAndreas Manios
Apr 27, 2017·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Stanislav N Tolkachjov
Oct 22, 2019·The American Journal of Dermatopathology·Gregory A GatesScott W Binder
Aug 27, 2010·The Journal of Spinal Cord Medicine·Sanjay YadiaJohn K Ratliff

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

The American Journal of Dermatopathology
Maria Victoria De Gálvez-ArandaAlfredo Matilla-Vicente
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
R M BremnesE A Jacobsen
Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
David Sable, Stephen N Snow
© 2021 Meta ULC. All rights reserved