PMID: 2422234Feb 1, 1986Paper

Pilomatrix carcinoma: an immunohistochemical comparison with benign pilomatrixoma and other benign cutaneous lesions of pilar origin

Journal of Cutaneous Pathology
C ManivelK Mukai

Abstract

Two new cases of pilomatrix carcinoma are reported. They were studied immunohistochemically for the presence of high and low-molecular weight cytokeratins, beta-2-microglobulin, S-100 protein, carcinoembryonic antigen, epithelial membrane antigen, blood group isoantigens, and peanut agglutinin binding. Results of these studies were compared with those obtained in immunohistologic analysis of 13 typical pilomatrixomas, and 4 other benign lesions with hair follicle differentiation. An attempt was made to correlate antigenic expression with malignant transformation; however, there were no consistent differences between the 2 groups. It would seem that immunocytochemistry is of no assistance in differential diagnosis between benign and malignant hair matrical tumors. Hence, the pathologist must rely on morphological criteria alone to make a diagnosis of pilomatrix carcinoma.

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Citations

Dec 27, 2006·Pathology Oncology Research : POR·Takeshi Kondo, Yoshio Tanaka
Mar 1, 1996·American Journal of Otolaryngology·M RotenbergD Brasnu
Aug 17, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R M BremnesE A Jacobsen
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Jan 22, 2002·The American Journal of Dermatopathology·D HardissonF Contreras
Apr 30, 2002·The American Journal of Dermatopathology·Maria Victoria De Gálvez-ArandaAlfredo Matilla-Vicente
Jun 8, 2010·The American Journal of Dermatopathology·Daniel LalichGarth Fraga
Jul 28, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·David Sable, Stephen N Snow
Nov 19, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jeffrey M MelanconShang I Brian Jiang
Apr 1, 1997·Journal of Cutaneous Pathology·S KadduH Kerl
May 13, 1999·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·J Caubet-BiaynaM Mas
Mar 10, 2004·Journal of Cutaneous Pathology·Assia BassarovaSvetlana Christova
Feb 1, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·A Neil CrowsonMartin C Mihm
Apr 30, 2017·Molecular and Clinical Oncology·Marios PapadakisAndreas Manios
Apr 15, 1993·Cancer·P SauJ H Graham
Dec 21, 2004·Journal of Cutaneous Pathology·Alexander J F LazarPhillip H McKee

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