PMID: 3762182Oct 1, 1986Paper

Pilomatrix carcinoma

Journal of Surgical Oncology
K T Chen, D R Taylor

Abstract

The clinicopathologic features of two cases of pilomatrix carcinoma are described and compared with those of the 11 previously reported cases. In contrast with its benign counterpart, pilomatrix carcinoma occurs in older patients and there is a male-predominating sex ratio. The rate of local recurrence is 60%. A single instance of distant metastasis occurred when the tumor recurred locally for the second time. Pilomatrix carcinoma can be accurately diagnosed histologically. The consistent features present in pilomatrix carcinoma but absent in the benign counterpart are increased mitotic activity and cytologic abnormalities including cellular and nuclear enlargement, and vesicular appearance of the nuclei. The primary lesion should be treated aggressively to prevent local recurrence, which may be a factor favoring distant tumor metastasis.

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Citations

Aug 17, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R M BremnesE A Jacobsen
Aug 14, 1999·The American Journal of Dermatopathology·J A CarlsonM C Mihm
Jan 22, 2002·The American Journal of Dermatopathology·D HardissonF Contreras
Apr 30, 2002·The American Journal of Dermatopathology·Maria Victoria De Gálvez-ArandaAlfredo Matilla-Vicente
Nov 25, 2003·The American Journal of Dermatopathology·Carlos MonteagudoCarmen Carda
Oct 1, 1994·International Journal of Dermatology·S KadduS Hödl
Nov 19, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jeffrey M MelanconShang I Brian Jiang
Nov 6, 2009·Veterinary Clinical Pathology·Karen JacksonRaquel M Walton
Apr 15, 1993·Cancer·P SauJ H Graham
Aug 27, 2010·The Journal of Spinal Cord Medicine·Sanjay YadiaJohn K Ratliff
Apr 4, 2017·The American Journal of Surgical Pathology·Liubov KyrpychovaDmitry V Kazakov
Dec 21, 2004·Journal of Cutaneous Pathology·Alexander J F LazarPhillip H McKee

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