Pilot randomized, controlled trial of a dyadic yoga program for glioma patients undergoing radiotherapy and their family caregivers

Neuro-oncology Practice
Kathrin MilburyLorenzo Cohen

Abstract

While the use of behavioral medicine in managing glioma patients' symptoms is not well studied, the high symptom burden in patients and their family caregivers is well established. We conducted a pilot randomized, controlled trial to examine the feasibility and preliminary efficacy of a dyadic yoga (DY) intervention as a supportive care strategy. Glioma patients undergoing radiotherapy and their caregivers were randomized to a 12-session DY or waitlist control (WLC) group. Prior to radiotherapy and randomization, both groups completed measures of cancer-related symptoms (MD Anderson Symptom Inventory-Brain Tumor module), depressive symptoms (Center for Epidemiological Studies-Depression measure), fatigue (Brief Fatigue Inventory), and overall quality of life (QOL; Medical Outcomes Study 36-item short-form survey). Dyads were reassessed at the last day of radiotherapy. Twenty patients (mean age: 46 years, 50% female, 80% WHO grade IV and caregivers (mean age: 50 years, 70% female, 50% spouses) participated in the trial. A priori feasibility criteria were met regarding consent (70%), adherence (88%), and retention (95%) rates. Controlling for relevant covariates, change score analyses revealed clinically significant improvements ...Continue Reading

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Citations

Oct 31, 2020·OncoTargets and Therapy·Guangjing HuangQian Fang
Apr 29, 2021·Journal of Neuro-oncology·Carolina X SandlerSandra C Hayes
Jun 1, 2021·Clinical Rehabilitation·Rita Lenoir Dit CaronMaxime Gilliaux
Oct 12, 2021·Health & Social Care in the Community·Milena HeinschFrances Kay-Lambkin

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