Pilot randomized controlled trial of functional electrical stimulation cycling exercise in people with multiple sclerosis with mobility disability

Multiple Sclerosis and Related Disorders
Thomas EdwardsL Pilutti

Abstract

Exercise training has been shown to be beneficial for persons with multiple sclerosis (MS). Adapted exercise modalities are needed to accommodate those with severe mobility impairment (Expanded Disability Status Scale [EDSS] scores 5.5-6.5). Functional electrical stimulation (FES) cycling is one such exercise modality; however, few studies have examined the feasibility and potential benefits of FES cycling for people with MS with severe mobility impairment. Determine the feasibility of FES cycling exercise for people with MS with severe mobility impairment, and the efficacy of FES cycling exercise for improving mobility and physiological fitness. 11 participants with MS with mobility impairment (EDSS = 5.5-6.5) were randomly allocated to FES cycling exercise (n = 6) or passive leg cycling (PLC; n = 5). Feasibility metrics included participant recruitment, retention, adherence, safety, and satisfaction. The primary mobility outcome was walking speed assessed by the Timed 25-Foot Walk (T25FW) test. The primary physiological fitness outcome was peak oxygen consumption (VO2peak), assessed using a cardiopulmonary exercise test. Eight participants completed the intervention (FES n = 4; PLC n = 4) with an adherence rate ≥80%. Three pa...Continue Reading

Citations

Nov 11, 2019·Current Treatment Options in Neurology·Lara A Pilutti, Robert W Motl
Nov 9, 2018·Multiple Sclerosis International·Maddalena SparacoSimona Bonavita
Dec 5, 2019·Physiology·Roger M EnokaJacques Duchateau
Dec 14, 2021·Frontiers in Medicine·Yong-Hui ZhangXue-Qiang Wang

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