PMID: 6106721Sep 1, 1980Paper

Pilus-dependent, double-stranded DNA bacteriophage for Caulobacter

Journal of Virology
D R Scholl, J D Jollick

Abstract

Caulobacter phage phi 6, previously reported to adsorb specifically to bacterial flagella, was shown here to attach to pili more frequently than to flagella. Phage phi 6 was shown to contain double-stranded DNA by circular dichroism spectroscopy and thermal denaturation accompanied by a hyperchromic shift at 260 nm. Morphologically, phage phi 6 fits group B2 (H.-W. Ackermann, in A. I. Laskin and H. A. Lechevalier, ed., Handbook of Microbiology, vol. 1, p. 638-643, 1973) with a long, noncontractile tail and an elongate head. Pilus-less mutants of the host Caulobacter vibrioides CV6 are phage phi 6 resistant, whereas flagellum-less mutants, which produce pili, are phage susceptible. Treatments of susceptible cells which remove or immobilize pili and flagella, e.g., blending or cyanide, inhibited phage phi 6 infection. Our evidence suggests that phage of phi 6 initiates infection in a manner similar to the pilus-specific phages for Pseudomonas described previously (D. E. Bradley, Virology 51:489-492, 1973; D. E. Bradley and T. L. Pitt, J. Gen. Virol. 24:1-15, 1974).

References

Jan 1, 1979·Journal of Bacteriology·R C Johnson, B Ely
Jan 1, 1975·Methods in Enzymology·T E WagnerD S Moore
Apr 1, 1971·Virology·N Agabian-Keshishian, L Shapiro
Jul 1, 1974·The Journal of General Virology·D E Bradley, T L Pitt
Mar 1, 1974·Journal of Bacteriology·C P Novotny, P Fives-Taylor
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Feb 1, 1974·The Journal of General Virology·J D Jollick, B L Wright
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Sep 1, 1964·Bacteriological Reviews·J S POINDEXTER
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Citations

Dec 7, 2013·Journal of Virology·Desislava A RaytchevaJonathan A King
May 27, 2011·Proceedings of the National Academy of Sciences of the United States of America·Ricardo C Guerrero-FerreiraElizabeth R Wright

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