Pilus-specific, lipid-containing bacteriophages PR4 and PR772: comparison of physical characteristics of genomes

The Journal of General Virology
W F Coetzee, P J Bekker

Abstract

The genomes of pilus-specific, lipid-containing phages PR4 and PR772 were studied electron microscopically. An identical mol. wt. of 10.9 x 10(6) was obtained. The genomes are unique (non-permuted) and have cohesive ends. From the similarities in size and denaturation maps of the genomes and failue to demonstrate non-homology in heteroduplexes, reported morphological ambiguities were clarified. The known serological difference between the phages could not be related to non-homology of their genomes. It is concluded that phages PR4 and PR772 are the same phage.

Related Concepts

RNA Conformation
Genome
RNA Denaturation
DNA, Viral
Bacteriophages
Genes, Viral
Heteroduplex DNA
Denaturation
Lipids
Bacterial Pilus

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