Pink Adipocytes

Trends in Endocrinology and Metabolism : TEM
Saverio Cinti

Abstract

Adipocytes are lipid-rich parenchymal cells contained in a very plastic organ, whose composition can undergo striking physiologic changes. In standard conditions the organ contains white and brown adipocytes which play opposite roles: lipid storage to meet metabolic requirements and lipid burning for thermogenesis, respectively. During chronic cold exposure, white adipocytes transdifferentiate to brown, to increase thermogenesis, whereas in conditions of chronic positive energy balance brown adipocytes transdifferentiate to white, to increase energy stores. During pregnancy, lactation, and post-lactation, subcutaneous white adipocytes convert to milk-producing glands formed by lipid-rich elements that can be defined as pink adipocytes. Recent fate-mapping data support the conversion of pink to brown adipocytes and the reversible conversion of brown adipocytes to myoepithelial cells of alveoli.

Citations

Mar 29, 2019·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Calvin C ChanSenad Divanovic
Jul 3, 2019·Cells·Luís Henrique CorrêaKelly Grace Magalhaes
Mar 4, 2020·Cells·Ilona RybinskaTiziana Triulzi
Jul 31, 2019·International Journal of Molecular Sciences·Mohammed El HafidiRoxana Carbó
May 24, 2020·International Journal of Molecular Sciences·Katarzyna ZorenaMałgorzata Mrugacz
Jun 17, 2020·The Biochemical Journal·Alice E Pollard, David Carling
Oct 28, 2019·Clinical Science·Tongxing Song, Shihuan Kuang
Oct 31, 2020·Frontiers in Endocrinology·Gabriella Simões HeynKelly Grace Magalhães
Jan 12, 2021·Frontiers in Endocrinology·Magdalena LeivaGuadalupe Sabio
Mar 16, 2021·Frontiers in Endocrinology·Miguel Hernandez-QuilesEric Kalkhoven
Mar 23, 2021·Reviews in Endocrine & Metabolic Disorders·Georgia ColleluoriSaverio Cinti
Jul 27, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Chung-Lin JiangFu-Jung Lin
Oct 14, 2021·Archives of Physiology and Biochemistry·Zoya TahergorabiMitra Moodi

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