Pipeline Embolization Device with or without Adjunctive Coil Embolization: Analysis of Complications from the IntrePED Registry.

AJNR. American Journal of Neuroradiology
M S ParkCameron G McDougall

Abstract

Flow diversion to treat cerebral aneurysms has revolutionized neurointerventional surgery. Because the addition of coils potentially increases the time and complexity of endovascular procedures, we sought to determine whether adjunctive coil use is associated with an increase in complications. Patients in the International Retrospective Study of Pipeline Embolization Device registry were divided into those treated with the Pipeline Embolization Device alone (n = 689 patients; n = 797 aneurysms; mean aneurysm size, 10.3 ± 7.6 mm) versus those treated with the Pipeline Embolization Device and concurrent coil embolization (n = 104 patients; n = 109 aneurysms; mean aneurysm size, 13.6 ± 7.8 mm). Patient demographics and aneurysm characteristics were examined. Rates of neurologic morbidity and mortality were compared between groups. The Pipeline Embolization Device with versus without coiling required a significantly longer procedure time (135.8 ± 63.9 versus 96.7 ± 46.2 min; P < .0001) and resulted in higher neurological morbidity (12.5% versus 7.8%; P = .13). These data suggest that either strategy represents an acceptable risk profile in the treatment of complex cerebral aneurysms and warrants further investigation.

References

Dec 15, 2010·AJNR. American Journal of Neuroradiology·P K NelsonD Fiorella
Dec 18, 2013·Journal of Neurointerventional Surgery·David DornbosEric Sauvageau
May 3, 2014·AJNR. American Journal of Neuroradiology·N ChalouhiP Jabbour
Jun 28, 2014·Journal of Neurointerventional Surgery·Min S ParkCameron G McDougall
Jul 24, 2014·Stroke; a Journal of Cerebral Circulation·Mario ZanatyPascal Jabbour
Oct 31, 2014·AJNR. American Journal of Neuroradiology·D F KallmesP Lylyk
Dec 31, 2014·Neurosurgery·Nohra ChalouhiPascal Jabbour
Jan 3, 2015·Journal of Neurosurgery. Pediatrics·Ramon NavarroRicardo A Hanel
Jan 15, 2015·Neurosurgery·Mario ZanatyPascal Jabbour
Jan 22, 2015·Journal of Neurointerventional Surgery·Francesco BrigantiFrancesco Maiuri
Jan 31, 2015·Journal of Neurosurgery·Nohra ChalouhiPascal Jabbour

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Citations

Sep 21, 2016·Expert Review of Medical Devices·Pedro Aguilar-SalinasRicardo Hanel
Sep 7, 2016·Journal of Neurointerventional Surgery·Anil K RoyCharles M Cawley
Dec 23, 2016·AJNR. American Journal of Neuroradiology·T P MadaelilA P Kansagra
Jun 5, 2017·World Neurosurgery·Nimer AdeebAjith J Thomas
Jan 31, 2018·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Kirill OrlovAnton Tasenko
Nov 1, 2016·Journal of Neurointerventional Surgery·Min S ParkCameron G McDougall
May 29, 2018·Journal of Neurointerventional Surgery·Matthew T BenderAlexander L Coon
Oct 18, 2018·Journal of Neurointerventional Surgery·Marie Teresa NawkaAndreas Maximilian Frölich
Oct 9, 2019·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Hannes LueckingStefan Lang
Dec 16, 2019·Neurosurgery·Anna Luisa KühnAjit S Puri
Dec 16, 2019·Neurosurgery·Phillip A BonneyBrian P Walcott
Jun 21, 2020·Neurosurgical Review·Andrew GriffinErik F Hauck
Mar 9, 2019·AJNR. American Journal of Neuroradiology·T P MadaelilF C Tong
Dec 1, 2020·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Timothy G WhiteHenry H Woo
Jun 30, 2019·Clinical Neurology and Neurosurgery·Yiping LiAzam Ahmed
Nov 24, 2020·Therapeutic Advances in Neurological Disorders·Bin LuoXinjian Yang
Jan 16, 2021·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Huibin KangJianmin Liu
May 15, 2021·Journal of Neurointerventional Surgery·Huibin KangXinjian Yang
Jun 16, 2021·World Neurosurgery·Tae Keun JeePyoung Jeon

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