PMID: 12783135Jun 5, 2003Paper

Pit pattern analysis by magnifying chromoendoscopy for the diagnosis of colorectal polyps

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Hui-Hsiung LiuJyh-Pyng Juch

Abstract

The development of magnifying chromoendoscopy has facilitated the observation of mucosal pit patterns. This study investigated the value of this technology in predicting the histologic findings of colorectal lesions. A total of 954 colorectal polyps were included. After identifying the lesions at colonoscopy, 0.2% indigocarmine solution was sprayed and then the zoom apparatus was switched to make a magnified view of the stained crypt orifice at a maximum 100 times magnification. The observed pit patterns were classified into 6 categories (I, II, IIIL, IIIS, IV, and V) according to Kudo's classification. Type I and II were designated as non-neoplastic patterns whereas other types were neoplastic. Correlation of the pit pattern with the findings of histologic examinations of resected or biopsied polyps was performed. There were 678 diminutive (</= 5 mm) polyps (71.1%) and 705 neoplastic polyps (73.9%), including 695 adenomas and 10 carcinomas. When comparing histologically confirmed neoplastic lesions to non-neoplastic lesions, prediction of neoplastic lesions by endoscopists based on magnifying chromoendoscopy had a sensitivity of 90.8%, a specificity of 72.7%, a positive predictive value of 90.4%, a negative predictive value of...Continue Reading

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