Pitfalls in the Diagnosis and Management of Invasive Pneumococcal Meningoencephalitis - What We Can Learn From a Case

Clinical Medicine Insights. Case Reports
Pascale S Grzonka, Raoul Sutter

Abstract

Invasive pneumococcal meningitis is a life-threatening infectious disease affecting the central nervous system. It continues to be the most common type of community-acquired acute bacterial meningitides. Despite advances in neuro-critical care, the case fatality rate remains high. Rapid diagnosis and initiation of antibiotic therapy precludes mortality and long-term neurological sequelae in survivors. However, not all cases are easily recognised, and unanticipated complications may impede optimal course and outcome. Here, we describe a case of invasive pneumococcal meningoencephalitis in a 65-year-old man with an unusual initial presentation and pitfalls in the course of the disease. We highlight the importance of early diagnosis and treatment as well as recognition and management of complications.

References

Jun 13, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Karen E ThomasVincent J Quagliarello
Oct 29, 2004·The New England Journal of Medicine·Diederik van de BeekMarinus Vermeulen
Feb 29, 2008·Neurology·E ZoonsD van de Beek
Aug 12, 2014·The Lancet Infectious Diseases·Rodrigo Lopez CastelblancoRodrigo Hasbun
Sep 25, 2015·Neurology·Raoul SutterSarah Tschudin-Sutter
Dec 15, 2015·The Lancet Infectious Diseases·Merijn W BijlsmaDiederik van de Beek
Apr 12, 2016·Nature Reviews. Neurology·Raoul SutterPeter W Kaplan
Oct 8, 2016·Critical Care : the Official Journal of the Critical Care Forum·Grete BuchholzMatthias Klein

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