Pituitary incidentalomas in paediatric population: Incidence and characteristics.

Clinical Endocrinology
Muhammed ShareefRoula Hourani

Abstract

To determine the incidence of pituitary incidentalomas in the paediatric population and among its different age subgroups as well as to identify the characteristics of these lesions. Additionally, we aim to give a perspective on the management and follow-up of these patients. We retrospectively studied MRI of children aged 18 years or below who underwent MRI with sellar region within their field of view between January 2010 and December 2018. Pituitary lesions were considered incidental according to the definition by the Endocrine Society. We reported the size, location and signal characteristics of each lesion. Medical charts of the subjects were reviewed for age, sex, the MRI indication and the hormonal assays levels. We identified 40 pituitary lesions of which 31 were incidental lesions. The incidence of pituitary incidentaloma in our cohort was 22 per 1000 patients with female predisposition ( 64.5%) and a mean age of 11 ± 6 years. Rathke's cleft cyst was the most prevalent lesion, accounting for 67.7% followed by cystic pituitary lesions and microadenomas. The most common indications for imaging were growth disturbance (12.9%) followed by headache (9.7%). Abnormal laboratory workup was present in 13% of the subjects. Incid...Continue Reading

References

Oct 1, 1990·The Journal of Clinical Endocrinology and Metabolism·S G KorenmanD Garza
Sep 1, 1994·Clinical Endocrinology·T Mindermann, C B Wilson
Nov 20, 1997·The American Journal of the Medical Sciences·G M NammourD C Aron
Dec 23, 1998·Endocrine Reviews·S L Asa, S Ezzat
Apr 20, 1999·Endocrinology and Metabolism Clinics of North America·P U Freda, K D Post
Jul 10, 2001·The Journal of Clinical Endocrinology and Metabolism·P ChansonG Schaison
Jul 27, 2004·Cancer·Shereen EzzatIan E McCutcheon
Dec 8, 2004·The Journal of Clinical Endocrinology and Metabolism·Ashild BjørneremGro K Rosvold Berntsen
Jun 16, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Carmine M ParianteRobin M Murray
May 6, 2006·European Journal of Radiology·Hadi Rokni-Yazdi, Houman Sotoudeh
Nov 6, 2007·The New England Journal of Medicine·Meike W VernooijAad van der Lugt
Sep 24, 2008·Endocrine-related Cancer·Gregory A KaltsasAshley B Grossman
Dec 1, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Mark E Molitch
Sep 3, 2010·Pituitary·Bradley D McDowellJanet A Schlechte
Jan 18, 2011·International Journal of Clinical Practice·P AnagnostisM Kita
Apr 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Pouyan FaminiShlomo Melmed
Apr 9, 2011·The Journal of Clinical Endocrinology and Metabolism·Pamela U FredaUNKNOWN Endocrine Society
Feb 22, 2012·Asian Journal of Neurosurgery·Amit Agrawal, S K Diwan
Sep 21, 2013·Pituitary·George A Scangas, Edward R Laws
Mar 25, 2015·Pituitary·César EstevesDavide Carvalho
Apr 3, 2016·European Journal of Endocrinology·Syed Ali ImranStan Van Uum
Apr 14, 2016·European Journal of Endocrinology·Vladimir VasilevAlbert Beckers
May 8, 2018·Journal of the American College of Radiology : JACR·Jenny K HoangDavid J Seidenwurm
Mar 1, 2010·Expert Review of Endocrinology & Metabolism·Dima Abdelmannan, David C Aron
Feb 21, 2019·The New England Journal of Medicine·K S Shivaprasad, Kollareddy Siddardha
Apr 28, 2019·Best Practice & Research. Clinical Endocrinology & Metabolism·Cesar Luiz BoguszewskiLeandro Kasuki
Aug 8, 2019·The Journal of Clinical Endocrinology and Metabolism·Vidhu V ThakerLaurie E Cohen

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Citations

Feb 23, 2021·Journal of Pediatric Endocrinology & Metabolism : JPEM·Jessica SchmittPaul B Kaplowitz
Jun 18, 2021·Journal of Neuroendocrinology·Emilia SbardellaUNKNOWN Talent group

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