PMID: 18407108Sep 1, 1992Paper

Pituitary lactotrophs: endocrine, paracrine, juxtacrine, and autocrine interactions

Trends in Endocrinology and Metabolism : TEM
Nira Ben-Jonathan, J W Liu

Abstract

The synthesis and release of PRL by the lactotrophs is subjected to multiple regulators that are classified into four categories: endocrine, paracrine, juxtacrine, and autocrine. Endocrine agents originate from the hypothalamus, gonads, and the posterior pituitary. Paracrine factors are produced by cells of the intermediate and anterior lobes. Juxtacrine transmitters arise from extracellular matrix and cells adjacent to the lactotrophs. Autocrine agents are synthesized by the lactotrophs themselves. Consequently, the overall secretory activity of the lactotrophs reflects a balance between local and distant releasing and inhibiting factors.

References

Mar 1, 1991·Endocrinology·W K SamsonF L Huang
Jan 26, 1990·Science·T YoshizawaI Kanazawa
Jan 1, 1985·Endocrine Reviews·N Ben-Jonathan
Mar 1, 1987·Endocrinology·F R Boockfor, L S Frawley
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Citations

Jun 1, 1995·Molecular and Cellular Endocrinology·F M PerezJ Schwartz
Mar 23, 2011·Nature Reviews. Endocrinology·Shlomo Melmed
Jun 26, 2007·Diabetes, Obesity & Metabolism·T BrandebourgN Ben-Jonathan
Dec 1, 1996·Cell Biology and Toxicology·F DemayM L Thieulant
Apr 1, 1994·Trends in Endocrinology and Metabolism : TEM·L Stephen Frawley
Aug 26, 2006·Peptides·Luciano Debeljuk, Mercedes Lasaga
Oct 1, 2005·Endocrinology·Eric R HugoNira Ben-Jonathan
Oct 4, 2000·Physiological Reviews·M E FreemanG Nagy
Jun 1, 1994·Journal of Endocrinological Investigation·J Schwartz, F M Perez

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