Pituitary-ovarian relationships in women approaching the menopause

Maturitas
T AbeM Suzuki

Abstract

With a view to evaluating pituitary-ovarian relationships in women approaching the menopause, serial determinations of basal body temperature (BBT) and of serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH) and oestradiol were performed in 5 pre-menopausal and 9 young women throughout a complete menstrual cycle. The hormone levels in the early follicular phase and on LH peak-days in the two groups were then compared. In the pre-menopausal group the age range was 43-45 yr and the length of the menstrual cycles investigated varied from 30-56 days, the BBT curves being biphasic. Two pre-menopausal women demonstrated concentrations of FSH and LH that were higher than those in the young women, even though their serum oestradiol levels in the early follicular phase remained within the upper and lower mean values observed in the young women. This finding confirmed that, in addition to reduced ovarian oestrogen secretion, another, as yet unknown, factor must exist, which can produce a rise in serum gonadotrophin levels in women approaching the menopause.

References

Apr 1, 1975·The Journal of Clinical Investigation·B M Sherman, S G Korenman
Apr 1, 1976·The Journal of Clinical Endocrinology and Metabolism·B M ShermanS G Korenman
Jul 1, 1973·Steroids·E YoussefnejadianI F Sommerville
Nov 1, 1968·Endocrinology·S E MonroeA R Midgley

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Citations

Dec 25, 2003·Schizophrenia Research·Raimo K R Salokangas
Oct 19, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Georgina E HaleHenry G Burger
Nov 29, 2005·Endocrinology and Metabolism Clinics of North America·Georgina E Hale, Henry G Burger
Dec 31, 2019·PloS One·Ruither O G CarolinoJanete Anselmo-Franci
Feb 1, 2021·Biology of Sex Differences·Wang-Zhong LiYan-Qun Xiang
Dec 1, 1989·Maturitas·S E ShidelerB L Lasley

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