PMID: 15348180Sep 7, 2004Paper

PIXE micro-beam mapping of metals in human peri-implant tissues

Journal of Materials Science. Materials in Medicine
P PassiG Moschini

Abstract

Previous investigations did not agree about the possible presence of titanium and other metals in the tissues around endosteal dental implants and joint prostheses. Indeed, while some authors reported diffusion of metals into the tissues, some others did not find evidence of this phenomenon. In the present study, four dental titanium implants, removed with the surrounding tissues from patients at various time intervals after the insertion, were studied by means of the micro-beam proton-induced X-ray emission (PIXE micro-beam) technique, which draws maps showing the tissue distribution of elements with a detection limit of about 1 ppm. One implant was built in commercially pure titanium, two others in titanium coated with titanium plasma spray, and the fourth in Ti-Al-V alloy. Their composition was confirmed by the PIXE micro-beam analyses. The removed samples were embedded in epoxy and processed with a cutting-grinding appliance, mounted on plastic holders, and ground up to a thickness of about 35 microm. Optical microscope examinations were also carried out, to compare the optical findings with the elemental maps obtained with the PIXE micro-beam. One implant, removed after 70 days because the patient had developed peri-implan...Continue Reading

Citations

Dec 22, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Daniel KrewskiVirginie Rondeau
Apr 5, 2016·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Magdalena GolasikWojciech Piekoszewski
Jun 28, 2005·Biochimica Et Biophysica Acta·Christopher J L Silwood, Martin Grootveld

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