Placental Doppler velocimetry in gestational diabetes mellitus

Journal of Perinatal Medicine
Marek PietrygaSaemundur Gudmundsson

Abstract

To evaluate if maternal glucose level and growth of the fetus were related to placental vascular impedance in pregnancy complicated by gestational diabetes mellitus. A retrospective study of 146 gestational diabetic women of which 117 needed insulin therapy. Glycosylated hemoglobin (HbA1c) was evaluated as well as umbilical and uterine artery Doppler velocimetry. The results were related to adverse outcome of pregnancy including newborn birthweight. Abnormal umbilical artery blood flow velocity was seen in 5% of the cases and abnormal uterine artery flow in 16%. Uterine and umbilical artery vascular impedance was significantly lower in macrosomic newborns. There was a poor correlation between HbA1c, vascular impedance and birthweight. There were 11 cases that developed preeclampsia, all having abnormal uterine artery Doppler and two abnormal umbilical artery Doppler. Uterine and umbilical artery vascular impedance in pregnancies complicated by gestational diabetes is related to birthweight and placental weight, but not to maternal HbA1c levels. Placental Doppler ultrasound does not seem to be of clinical value for fetal surveillance in these pregnancies unless the pregnancy is complicated by preeclampsia and/or intrauterine fet...Continue Reading

References

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Citations

Aug 13, 2011·Diabetology & Metabolic Syndrome·Marilza Vc RudgeIracema Mp Calderon
Nov 7, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Rocío Quintero-PradoJose Luis Bartha
Dec 5, 2015·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Keziban DoğanMurat Ekin
Feb 28, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M D SavvidouK H Nicolaides
Jul 26, 2008·Seminars in Perinatology·Alessandro Ghidini, Anna Locatelli
Apr 8, 2011·Paediatric and Perinatal Epidemiology·Jodie KatonEdith Miller
Jul 24, 2013·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Enrique Guzmán-GutiérrezLuis Sobrevia
Aug 20, 2009·Diabetes Care·Noirin E RussellF M McAuliffe
Nov 22, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ali YeşilHüseyin Cengiz
Nov 25, 2018·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Andrea M A DantasJean C Silva
Nov 22, 2011·Current Diabetes Reports·M GausterU Hiden
Jun 2, 2018·Pflügers Archiv : European journal of physiology·Hongliang LiWon Sun Park
Mar 14, 2007·Current Opinion in Obstetrics & Gynecology

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