PMID: 15381911Sep 24, 2004Paper

Placental yolk sac tumor with divergent endodermal differentiation

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
Taka-Aki MatsuyamaHidekazu Ota

Abstract

We report an intraplacental germ cell tumor that was an incidental finding in the placenta of a 34-year-old woman. On pathologic examination, the 4.0-cm tumor was well circumscribed with a thin fibrous capsule. It exhibited three major histologic patterns within a mesenchyme-like myxoid background: a primitive endodermal component, a well-differentiated enteric glandular endodermal component, and a component of fetal hepatic tissue. The primitive endodermal component, the hepatic component, and many parts of the enteric endodermal glandular component were immunoreactive for alpha-fetoprotein. We considered the lesion to be a unique example of a placental yolk sac tumor and only the second reported case of a placental yolk sac tumor.

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Citations

Nov 15, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·N J Sebire, E Jauniaux
Dec 21, 2007·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Eva F KarpfSigrid Regauer
Oct 20, 2011·Histopathology·Francisco F NogalesAlina Nicolae
Jul 23, 2016·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Hadi ShojaeiRaymond W Redline
Jun 9, 2017·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Rasleen SalujaDebra S Heller
Jul 23, 2020·Fetal and Pediatric Pathology·Nora Schaumann, Kais Hussein

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