Plain to point network reduced graphene oxide-activated carbon composites decorated with platinum nanoparticles for urine glucose detection

Scientific Reports
Mohammad Faruk Hossain, Jae Y Park

Abstract

In this study, a hydrothermal technique was applied to synthesize glucose-treated reduced graphene oxide-activated carbon (GRGO/AC) composites. Platinum nanoparticles (PtNP) were electrochemically deposited on the modified GRGO/AC surface, and chitosan-glucose oxidase (Chit-GOx) composites and nafion were integrated onto the modified surface of the working electrode to prepare a highly sensitive glucose sensor. The fabricated biosensor exhibited a good amperometric response to glucose in the detection range from 0.002 mM to 10 mM, with a sensitivity of 61.06 μA/mMcm(2), a short response time (4 s) and a low detection limit of 2 μM (signal to noise ratio is 3). The glucose sensor exhibited a negligible response to interference and good stability. In addition, the glucose levels in human urine were tested in order to conduct a practical assessment of the proposed sensor, and the results indicate that the sensor had superior urine glucose recognition. These results thus demonstrate that the noble nano-structured electrode with a high surface area and electrocatalytic activity offers great promise for use in urine glucose sensing applications.

References

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Citations

Oct 26, 2016·Analytical Chemistry·Emilia Witkowska NeryMartin Jönsson-Niedziółka
Nov 15, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Shanmugam MahalingamYoung-Ho Ahn
Oct 20, 2018·ACS Applied Materials & Interfaces·Xiangming LiQi An

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Methods Mentioned

BETA
biosensors
biosensor
chip
scanning electron microscopy

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