Plain-water intake and risk of type 2 diabetes in young and middle-aged women.

The American Journal of Clinical Nutrition
An PanFrank B Hu

Abstract

The replacement of caloric beverages such as sugar-sweetened beverages (SSBs) and fruit juices with noncaloric beverages such as plain water has been recommended for diabetes prevention. We evaluated the relation of plain-water intake and the substitution of plain water for SSBs and fruit juices with incident type 2 diabetes (T2D) in US women. We prospectively followed 82,902 women in the Nurses' Health Study II who were free of diabetes, cardiovascular disease, or cancer at baseline. Diet, including various beverages, was assessed by using validated food-frequency questionnaires and updated every 4 y. Incident T2D was confirmed by using a validated supplementary questionnaire. We used a 4-y lagged analysis to minimize reverse causation (ie, increased water consumption that was due to early stage of diabetes). During 1,115,427 person-years of follow-up, we documented 2718 incident T2D cases. Plain-water intake was not associated with T2D risk in the multivariable-adjusted model that included age, BMI, diet, and lifestyle factors; RRs (95% CIs) across categories (<1, 1, 2-3, 4-5, and ≥6 cups/d) were 1.00, 0.93 (0.82, 1.05), 0.93 (0.83, 1.05), 1.09 (0.96, 1.24), and 1.06 (0.91, 1.23), respectively (P-trend = 0.15). We estimated t...Continue Reading

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Citations

Feb 27, 2013·Nature Reviews. Nephrology·Lise BankirEberhard Ritz
Jan 16, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A PanF B Hu
Jul 26, 2014·The International Journal of Behavioral Nutrition and Physical Activity·Vivian M van de GaarHein Raat
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Jun 30, 2021·Diabetes & Metabolic Syndrome·Nasim JanbozorgiMaryam Safabakhsh

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