Planar cell polarity in organ formation.

Current Opinion in Cell Biology
Deborah J HendersonCharlotte H Dean

Abstract

The planar cell polarity (PCP) pathway controls a variety of morphological events across many species. During embryonic development, the PCP pathway regulates coordinated behaviour of groups of cells to direct morphogenetic processes such as convergent extension and collective cell migration. In this review we discuss the increasingly prominent role of the PCP pathway in organogenesis, focusing on the lungs, kidneys and heart. We also highlight emerging evidence that PCP gene mutations are associated with adult diseases.

Citations

Aug 21, 2018·The Journal of Pathology·Eugenia PapakrivopoulouDavid A Long
Jun 21, 2019·Cellular and Molecular Life Sciences : CMLS·Mathias Heikenwalder, Anna Lorentzen
Jan 15, 2020·ELife·Bomsoo ChoJeffrey D Axelrod
Aug 9, 2019·Annual Review of Cell and Developmental Biology·Mithila Burute, Lukas C Kapitein
Nov 17, 2020·Frontiers in Cell and Developmental Biology·Sek-Shir CheongCharlotte H Dean
Dec 15, 2020·Development·Krishnanand PadmanabhanChen Luxenburg
Mar 16, 2021·Frontiers in Physiology·Eugenia PapakrivopoulouDavid A Long
Mar 28, 2021·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Qinlong HaoJian Zou
Jun 8, 2021·Acta Neuropathologica Communications·Florent MarguetPascale Saugier-Veber
Jul 24, 2021·Cell Communication and Signaling : CCS·Jeffrey D Amack
Aug 10, 2021·Frontiers in Cell and Developmental Biology·Laura Maeso-AlonsoMaria C Marin

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