Planimetric hematoma measurement in patients with intraventricular hemorrhage: is total volume a preferred target for reliable analysis?

Stroke; a Journal of Cerebral Circulation
Dar DowlatshahiPREDICT/Sunnybrook ICH-CTA study group

Abstract

Reliable quantification of both intracerebral hemorrhage and intraventricular hemorrhage (IVH) volume is important for hemostatic trials. We evaluated the reliability of computer-assisted planimetric volume measurements of IVH. Computer-assisted planimetry was used to quantify IVH volume. Five raters measured IVH volumes, total (intracerebral hemorrhage+IVH) volumes, and Graeb scores from 20 randomly selected computed tomography scans twice. Estimates of interrater and intrarater reliability were calculated and expressed as an intrarater correlation coefficient and an absolute minimum detectable difference. Planimetric IVH volume analysis had excellent intra- and interrater agreement (intrarater correlation coefficient, 0.96 and 0.92, respectively), which was superior to the Graeb score (intrarater correlation coefficient, 0.88 and 0.83). Minimum detectable differences for intra- and interrater volumes were 12.1 mL and 17.3 mL, and were dependent on the total size of the hematoma; hematomas smaller than the median 43.8 mL had lower minimum detectable differences, whereas those larger than the median had higher minimum detectable differences. Planimetric total hemorrhage volume analysis had the best intra- and interrater agreeme...Continue Reading

References

Apr 26, 2006·Neurology·S M DavisUNKNOWN Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators
Apr 9, 2008·Lancet Neurology·Craig S AndersonUNKNOWN INTERACT Investigators
Oct 6, 2009·Journal of Clinical Epidemiology·Dan TurnerGordon H Guyatt
Feb 25, 2011·Neurology·D DowlatshahiUNKNOWN VISTA Collaboration
May 26, 2011·International Journal of Stroke : Official Journal of the International Stroke Society·Jayme C KosiorUNKNOWN PREDICT/Sunnybrook CTA ICH study investigators

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Citations

Mar 7, 2014·PloS One·Santanu ChakrabortyDar Dowlatshahi
Jan 13, 2015·International Journal of Stroke : Official Journal of the International Stroke Society·Satu MustanojaTurgut Tatlisumak
Nov 29, 2014·Internal and Emergency Medicine·Silvia RicciSimona Sacco
Jan 20, 2016·International Journal of Stroke : Official Journal of the International Stroke Society·Dar DowlatshahiUNKNOWN PREDICT/Sunnybrook ICH CTA study group
Jan 19, 2018·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Jay F YuDaniel L Cooke
Nov 2, 2013·Stroke; a Journal of Cerebral Circulation·Dar DowlatshahiUNKNOWN Ottawa Stroke Research Group
Mar 31, 2016·Stroke; a Journal of Cerebral Circulation·Binli WangMin Lou
Feb 20, 2016·Stroke; a Journal of Cerebral Circulation·David Rodriguez-LunaUNKNOWN PREDICT/Sunnybrook ICH CTA study group
Aug 1, 2019·Annals of Neurology·Andrea MorottiUNKNOWN International NCCT ICH Study Group
Nov 19, 2019·Stroke; a Journal of Cerebral Circulation·Natasha IronsideEdward Sander Connolly
Aug 3, 2019·Neurology·Vignan YogendrakumarUNKNOWN the PREDICT/Sunnybrook CTA Study Group
Feb 23, 2020·Stroke; a Journal of Cerebral Circulation·Vignan YogendrakumarUNKNOWN PREDICT/Sunnybrook CTA Study Group
Nov 3, 2020·International Journal of Stroke : Official Journal of the International Stroke Society·Ronda LunDar Dowlatshahi

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