Planning for selective amygdalohippocampectomy involving less neuronal fiber damage based on brain connectivity using tractography

Neural Regeneration Research
Seung-Hak LeeHyunjin Park

Abstract

Temporal lobe resection is an important treatment option for epilepsy that involves removal of potentially essential brain regions. Selective amygdalohippocampectomy is a widely performed temporal lobe surgery. We suggest starting the incision for selective amygdalohippocampectomy at the inferior temporal gyrus based on diffusion magnetic resonance imaging (MRI) tractography. Diffusion MRI data from 20 normal participants were obtained from Parkinson's Progression Markers Initiative (PPMI) database (www.ppmi-info.org). A tractography algorithm was applied to extract neuronal fiber information for the temporal lobe, hippocampus, and amygdala. Fiber information was analyzed in terms of the number of fibers and betweenness centrality. Distances between starting incisions and surgical target regions were also considered to explore the length of the surgical path. Middle temporal and superior temporal gyrus regions have higher connectivity values than the inferior temporal gyrus and thus are not good candidates for starting the incision. The distances between inferior temporal gyrus and surgical target regions were shorter than those between middle temporal gyrus and target regions. Thus, the inferior temporal gyrus is a good candid...Continue Reading

References

Jan 1, 1992·Trends in Neurosciences·M A Goodale, A D Milner
Jun 1, 1982·Surgical Neurology·H G Wieser, M G Yaşargil
Mar 7, 1996·The New England Journal of Medicine·J Engel
Apr 19, 2000·Journal of Cognitive Neuroscience·R Cabeza, L Nyberg
Jun 5, 2001·Acta Psychologica·S H Creem, D R Proffitt
Aug 4, 2001·The New England Journal of Medicine·S WiebeUNKNOWN Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group
Sep 26, 2003·The New England Journal of Medicine·Bernard S Chang, Daniel H Lowenstein
Sep 1, 2004·The American Journal of Psychiatry·Toshiaki OnitsukaRobert W McCarley
Jul 6, 2007·PloS One·Patric HagmannJean-Philippe Thiran
Oct 3, 2007·Nonlinear Biomedical Physics·Cornelis J Stam, Jaap C Reijneveld
Sep 2, 2008·Neurosurgical Focus·Badih Adada
Feb 4, 2009·IEEE Transactions on Medical Imaging·Maxime DescoteauxAlfred Anwander
Feb 5, 2009·Nature Reviews. Neuroscience·Ed Bullmore, Olaf Sporns
Sep 14, 2010·Brain Research·Roger J JouAntonio Y Hardan
Aug 13, 2011·Epilepsy Research·Ashalatha RadhakrishnanKurupath Radhakrishnan
Sep 21, 2011·Progress in Neurobiology·UNKNOWN Parkinson Progression Marker Initiative
Oct 8, 2011·NeuroImage·Mark JenkinsonStephen M Smith
Oct 18, 2011·Journal of Neuroscience Methods·Leila CammounPatric Hagmann
Jan 18, 2012·NeuroImage·Bruce Fischl
Sep 8, 2012·Epilepsy Research and Treatment·David Spencer, Kim Burchiel
Dec 29, 2012·PloS One·Alessandro DaducciJean-Philippe Thiran
Jan 9, 2013·Epilepsia·Jennifer FaberBernd Weber
Aug 6, 2013·Brain and Language·Jennifer S W Campbell, G Bruce Pike

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

FSL
FSL ( Functional Magnetic Resonance Imaging of the Brain Softw...
Diffusion Toolkit
CMTK
Freesurfer
MATLAB
Functional Magnetic Resonance Imaging of the Brain Software Li...

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.