Plant dipeptidyl peptidase-IV inhibitors as antidiabetic agents: a brief review

Future Medicinal Chemistry
Gulmira TurduMadina Kabas

Abstract

Diabetes mellitus is an increasing public health problem in the world. Type 2 diabetes is the most common type of diabetes whose complications contribute to its high death rate. It seriously impacts healthcare systems and patients' quality of life. Therefore, effective measures and new treatment strategies are needed to solve this increasingly serious global problem. In recent years, inhibition of dipeptidyl peptidase IV (DPP-IV) has emerged as a new treatment option for Type 2 diabetes. This article reviews various plant DPP-IV inhibitors that showed inhibition toward enzyme as a major target for the management of Type 2 diabetes. These studies can contribute to the future development of DPP-IV inhibitors as drugs.

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Aug 4, 2020·Critical Reviews in Analytical Chemistry·Barbora LegerskáStanislav Miertuš
Jul 25, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mayadah Bashir ShehadehAla' Mustafa Abu-Odeh

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