Plant lncRNAs are enriched in and move systemically through the phloem in response to phosphate deficiency

Journal of Integrative Plant Biology
Zhaoliang ZhangW J Lucas

Abstract

In response to phosphate (Pi) deficiency, it has been shown that micro-RNAs (miRNAs) and mRNAs are transported through the phloem for delivery to sink tissues. Growing evidence also indicates that long non-coding RNAs (lncRNAs) are critical regulators of Pi homeostasis in plants. However, whether lncRNAs are present in and move through the phloem, in response to Pi deficiency, remains to be established. Here, using cucumber as a model plant, we show that lncRNAs are enriched in the phloem translocation stream and respond, systemically, to an imposed Pi-stress. A well-known lncRNA, IPS1, the target mimic (TM) of miRNA399, accumulates to a high level in the phloem, but is not responsive to early Pi deficiency. An additional 24 miRNA TMs were also detected in the phloem translocation stream; among them miRNA171 TMs and miR166 TMs were induced in response to an imposed Pi stress. Grafting studies identified 22 lncRNAs which move systemically into developing leaves and root tips. A CU-rich PTB motif was further identified in these mobile lncRNAs. Our findings revealed that lncRNAs respond to Pi deficiency, non-cell-autonomously, and may act as systemic signaling agents to coordinate early Pi deficiency signaling, at the whole-plant ...Continue Reading

References

Mar 19, 2005·The Plant Journal : for Cell and Molecular Biology·Valerie HaywoodWilliam J Lucas
May 4, 2006·Annual Review of Plant Biology·Tony J Lough, William J Lucas
Jun 13, 2006·BMC Bioinformatics·Koji KadotaKentaro Shimizu
Oct 31, 2006·Proceedings of the National Academy of Sciences of the United States of America·Surekha Katiyar-AgarwalHailing Jin
Jul 24, 2007·Nature Genetics·José Manuel Franco-ZorrillaJavier Paz-Ares
Nov 9, 2007·The Plant Journal : for Cell and Molecular Biology·Bikram Datt PantWolf-Rüdiger Scheible
Apr 9, 2008·Plant Physiology·Shu-I LinTzyy-Jen Chiou
Oct 22, 2008·Molecular & Cellular Proteomics : MCP·Ming-Kuem LinWilliam J Lucas
Mar 6, 2009·Genome Biology·Ben LangmeadSteven L Salzberg
Nov 3, 2009·Nature Genetics·Sanwen HuangSonggang Li
Jan 30, 2010·Bioinformatics·Aaron R Quinlan, Ira M Hall
Apr 15, 2010·BMC Plant Biology·Anja BuhtzJulia Kehr
Sep 3, 2010·The Plant Journal : for Cell and Molecular Biology·Yi MaWilliam J Lucas
Mar 5, 2011·Annual Review of Plant Biology·Tzyy-Jen Chiou, Shu-I Lin
Oct 14, 2011·Nature·Jonathan A FoleyDavid P M Zaks
Nov 23, 2011·Trends in Plant Science·Eun-Deok Kim, Sibum Sung
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jihua DingQifa Zhang
Aug 29, 2012·Journal of Integrative Plant Biology·Michitaka NotaguchiWilliam J Lucas
Oct 30, 2012·Bioinformatics·Alexander DobinThomas R Gingeras
Nov 30, 2012·Nucleic Acids Research·Christian QuastFrank Oliver Glöckner
Mar 7, 2013·Journal of Integrative Plant Biology·William J LucasPradeep Kachroo
May 3, 2013·Nature·Julian I SchroederDale Sanders
Jan 15, 2014·Journal of Integrative Plant Biology·Zhaoliang ZhangWilliam J Lucas
Mar 1, 2014·Genome Biology·Lin LiGary J Muehlbauer
Apr 4, 2014·Bioinformatics·Anthony M BolgerBjoern Usadel
Jul 2, 2014·Proceedings of the National Academy of Sciences of the United States of America·Yuqiu WangXing Wang Deng
Jul 22, 2014·The Plant Journal : for Cell and Molecular Biology·Wenna ZhangFriedrich Kragler
Jul 30, 2014·Developmental Cell·Florian BardouMartin Crespi
Sep 18, 2014·The Plant Journal : for Cell and Molecular Biology·Byung-Kook HamWilliam J Lucas

❮ Previous
Next ❯

Citations

Aug 14, 2019·Annual Review of Cell and Developmental Biology·Yu YuYueqin Chen
Mar 28, 2020·Functional & Integrative Genomics·Tongqiang FanYoujun Huang
Sep 6, 2019·International Journal of Molecular Sciences·Chiara Pagliarani, Giorgio Gambino
Oct 8, 2020·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Xiaoxu ZhouYushi Luan
Sep 22, 2020·Bioscience Reports·Amanda M Koenig, Susanne Hoffmann-Benning
Jun 22, 2020·Plant Science : an International Journal of Experimental Plant Biology·Aarohi SummanwarNat N V Kav
Mar 9, 2021·Journal of Experimental Botany·Kirtikumar R KondhareAnjan K Banerjee
Dec 1, 2021·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Zhengfeng ZhangBenze Xiao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.