PLANT MITOCHONDRIA AND OXIDATIVE STRESS: Electron Transport, NADPH Turnover, and Metabolism of Reactive Oxygen Species

Annual Review of Plant Physiology and Plant Molecular Biology
Ian M Moller

Abstract

The production of reactive oxygen species (ROS), such as O2- and H2O2, is an unavoidable consequence of aerobic metabolism. In plant cells the mitochondrial electron transport chain (ETC) is a major site of ROS production. In addition to complexes I-IV, the plant mitochondrial ETC contains a non-proton-pumping alternative oxidase as well as two rotenone-insensitive, non-proton-pumping NAD(P)H dehydrogenases on each side of the inner membrane: NDex on the outer surface and NDin on the inner surface. Because of their dependence on Ca2+, the two NDex may be active only when the plant cell is stressed. Complex I is the main enzyme oxidizing NADH under normal conditions and is also a major site of ROS production, together with complex III. The alternative oxidase and possibly NDin(NADH) function to limit mitochondrial ROS production by keeping the ETC relatively oxidized. Several enzymes are found in the matrix that, together with small antioxidants such as glutathione, help remove ROS. The antioxidants are kept in a reduced state by matrix NADPH produced by NADP-isocitrate dehydrogenase and non-proton-pumping transhydrogenase activities. When these defenses are overwhelmed, as occurs during both biotic and abiotic stress, the mitoc...Continue Reading

References

Jul 1, 1979·Physiological Reviews·B ChanceA Boveris
Dec 1, 1979·Canadian Journal of Biochemistry·G P Arron, G E Edwards
May 1, 1978·Archives of Biochemistry and Biophysics·P R Rich, W D Bonner
Aug 9, 1976·Biochemical and Biophysical Research Communications·P R RichA L Moore
May 1, 1992·The Plant Journal : for Cell and Molecular Biology·J D Williamson, J G Scandalios
Feb 20, 1992·Journal of Molecular Biology·Y KohwiT Kohwi-Shigematsu
Jul 8, 1991·Biochimica Et Biophysica Acta·S PuntaruloA Boveris
Dec 5, 1991·European Journal of Biochemistry·A G Rasmusson, I M Møller
Dec 1, 1991·Journal of Bioenergetics and Biomembranes·R G Hansford
Aug 23, 1991·Biochimica Et Biophysica Acta·A L Moore, J N Siedow
Nov 10, 1988·Biochimica Et Biophysica Acta·M G RedinbaughJ G Scandalios
Apr 1, 1989·European Journal of Biochemistry·G von HeijneR G Herrmann
Mar 1, 1985·Archives of Biochemistry and Biophysics·J F TurrensA L Lehninger
Aug 15, 1988·The Biochemical Journal·J B Hoek, J Rydström
Jan 18, 1973·Biochimica Et Biophysica Acta·R DouceW D Bonner
Nov 1, 1980·The Biochemical Journal·J F Turrens, A Boveris
Nov 30, 1982·Biochemical and Biophysical Research Communications·A L Moore, K E Akerman
May 24, 1995·Biochimica Et Biophysica Acta·A Meister
Jun 1, 1994·The International Journal of Biochemistry·A Del CorsoU Mura
Aug 1, 1993·Journal of Bioenergetics and Biomembranes·I M MøllerK M Fredlund
Dec 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·A A al-Robai
Aug 1, 1995·Journal of Bioenergetics and Biomembranes·K L Soole, R I Menz
Apr 19, 1996·The Journal of Biological Chemistry·M NeuburgerR Douce
Feb 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·H WadaJ Ohlrogge
Apr 1, 1997·Proceedings of the National Academy of Sciences of the United States of America·S GutierresR De Paepe
Sep 20, 1997·Nature·M LaloiD Ricquier

❮ Previous
Next ❯

Citations

Nov 15, 2005·Planta·Abir U IgamberdievRobert D Hill
Oct 9, 2007·Protoplasma·Vesna Hadzi-Tasković SukalovićM Vuletić
Jun 19, 2010·Protoplasma·Devarshi S Selote, Renu Khanna-Chopra
Dec 1, 2006·Functional & Integrative Genomics·Grant R CramerJohn C Cushman
Sep 5, 2012·Journal of Bioenergetics and Biomembranes·Hoang Thi Kim Hong, Akihiro Nose
Dec 18, 2004·Plant Molecular Biology·A Harvey MillarHans-Peter Braun
Aug 10, 2006·Plant Molecular Biology·Roman A VolkovFriedrich Schöffl
Mar 22, 2013·Plant Molecular Biology·Shiping TianBoqiang Li
Aug 14, 2010·Photosynthesis Research·Yves Lemoine, Benoît Schoefs
Dec 8, 2011·Environmental Science and Pollution Research International·Huagang HuangTingxuan Li
May 12, 2009·Journal of Biosciences·Paolo Zuccarini
Jul 1, 2008·Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology·Anukriti Atreya, Sujata Bhargava
Sep 7, 2011·Biochimica Et Biophysica Acta·Juri DubininFrank Colditz

❮ Previous
Next ❯

Methods Mentioned

BETA
gel-filtration

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved