Plant mitochondrial Complex I composition and assembly: A review

Biochimica Et Biophysica Acta
Nitya SubrahmanianPatrice Paul Hamel

Abstract

In the mitochondrial inner membrane, oxidative phosphorylation generates ATP via the operation of several multimeric enzymes. The proton-pumping Complex I (NADH:ubiquinone oxidoreductase) is the first and most complicated enzyme required in this process. Complex I is an L-shaped enzyme consisting of more than 40 subunits, one FMN molecule and eight Fe-S clusters. In recent years, genetic and proteomic analyses of Complex I mutants in various model systems, including plants, have provided valuable insights into the assembly of this multimeric enzyme. Assisted by a number of key players, referred to as "assembly factors", the assembly of Complex I takes place in a sequential and modular manner. Although a number of factors have been identified, their precise function in mediating Complex I assembly still remains to be elucidated. This review summarizes our current knowledge of plant Complex I composition and assembly derived from studies in plant model systems such as Arabidopsis thaliana and Chlamydomonas reinhardtii. Plant Complex I is highly conserved and comprises a significant number of subunits also present in mammalian and fungal Complexes I. Plant Complex I also contains additional subunits absent from the mammalian and f...Continue Reading

References

Jul 19, 1994·Proceedings of the National Academy of Sciences of the United States of America·B E Alber, J G Ferry
Mar 19, 1996·Proceedings of the National Academy of Sciences of the United States of America·G BurgerM W Gray
Apr 1, 1996·Biological Chemistry Hoppe-Seyler·B LippokM Unseld
Apr 1, 1997·Proceedings of the National Academy of Sciences of the United States of America·S GutierresR De Paepe
Jun 19, 1998·Biochimica Et Biophysica Acta·A G RasmussonL Grohmann
Aug 17, 1999·Current Opinion in Structural Biology·N Grigorieff
Jul 13, 2000·Journal of Molecular Biology·O EmanuelssonG von Heijne
Sep 27, 2000·Biochimica Et Biophysica Acta·S J Kerscher
Aug 11, 2001·Biochemical Society Transactions·C RemacleR F Matagne
Jun 27, 2002·The Plant Cell·Byeong-ha LeeJian-Kang Zhu
Jul 18, 2002·Proceedings of the National Academy of Sciences of the United States of America·Blanca BarqueraRobert B Gennis
Dec 7, 2002·The Plant Cell·Olga V KarpovaKathleen J Newton
Feb 22, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jaap J van HellemondAloysius G M Tielens
Mar 20, 2003·Molecular & Cellular Proteomics : MCP·Joe CarrollJohn E Walker
Jul 3, 2003·Biochimica Et Biophysica Acta·Judy HirstJohn E Walker
Oct 14, 2003·Plant Physiology·A Harvey MillarChristine H Foyer
Mar 17, 2004·Molecular Phylogenetics and Evolution·Alastair G B Simpson, Andrew J Roger
Sep 25, 2004·International Journal of Systematic and Evolutionary Microbiology·David MoreiraKeith Vickerman
Dec 14, 2004·Microbiology and Molecular Biology Reviews : MMBR·Ana M P MeloMiguel Teixeira
Dec 18, 2004·Plant Molecular Biology·Gustavo ParisiEduardo Zabaleta

❮ Previous
Next ❯

Citations

Apr 25, 2016·Biochimica Et Biophysica Acta·Ulrich Uli Brandt, Volker Zickermann
Dec 25, 2016·Plant & Cell Physiology·Atsushi TakabayashiAyumi Tanaka
Mar 7, 2017·Physiologia Plantarum·Jennifer SenklerHans-Peter Braun
Mar 29, 2018·Journal of Experimental Botany·Kapuganti Jagadis GuptaAbir U Igamberdiev
Sep 1, 2018·The Journal of Biological Chemistry·Matus ValachGertraud Burger
Oct 23, 2018·The Plant Journal : for Cell and Molecular Biology·Joanna LigasEtienne H Meyer
Oct 6, 2017·Journal of Integrative Plant Biology·Xiaojie LiJinsheng Lai
Jul 19, 2018·The Biochemical Journal·Abi S GhifariMonika W Murcha
May 20, 2020·International Journal of Molecular Sciences·Yumi Nakai, Akiko Maruyama-Nakashita
Feb 7, 2020·Plant Direct·Nitya SubrahmanianPatrice Paul Hamel
Oct 17, 2020·Nature Communications·Heddy SoufariYaser Hashem
Dec 12, 2020·Frontiers in Plant Science·Toby E Newman, Mark C Derbyshire
Mar 9, 2021·The Plant Journal : for Cell and Molecular Biology·Sofia Shevtsov-TalOren Ostersetzer-Biran

❮ Previous
Next ❯

Related Concepts

Related Feeds

Archaeogenetics

Recent advances in genomic sequencing has led to the discovery of new strains of Archaea and shed light on their evolutionary history. Discover the latest research on Archaeogenetics here.