Plant nucleolar DNA: Green light shed on the role of Nucleolin in genome organization

Nucleus
Claire Picart, Frédéric Pontvianne

Abstract

The nucleolus forms as a consequence of ribosome biogenesis, but it is also implicated in other cell functions. The identification of nucleolus-associated chromatin domains (NADs) in animal and plant cells revealed the presence of DNA sequences other than rRNA genes in and around the nucleolus. NADs display repressive chromatin signatures and harbour repetitive DNA, but also tRNA genes and RNA polymerase II-transcribed genes. Furthermore, the identification of NADs revealed a specific function of the nucleolus and the protein Nucleolin 1 (NUC1) in telomere biology. Here, we discuss the significance of these data with regard to nucleolar structure and to the role of the nucleolus and NUC1 in global genome organization and stability.

References

Jun 1, 1997·Chromosoma·S A Gerbi, A Borovjagin
Feb 19, 2000·Biochemical and Biophysical Research Communications·A PolliceE Gilson
Oct 18, 2002·Proceedings of the National Academy of Sciences of the United States of America·Paul FranszIngo Schubert
Feb 9, 2007·The Plant Journal : for Cell and Molecular Biology·Hisae KojimaKenzo Nakamura
Feb 27, 2007·Cell·Tony Kouzarides
Jun 15, 2007·Nucleic Acids Research·Takashi Ishida, Kengo Kinoshita
Oct 14, 2009·Proceedings of the National Academy of Sciences of the United States of America·Silvana Paredes, Keith A Maggert
Feb 6, 2010·Science·Satoru IdeTakehiko Kobayashi
Apr 3, 2010·PLoS Genetics·Attila NémethGernot Längst
Nov 26, 2010·Cold Spring Harbor Perspectives in Biology·Thoru Pederson
Nov 29, 2014·Frontiers in Genetics·Veit SchubertIngo Schubert
Mar 11, 2015·The Plant Journal : for Cell and Molecular Biology·Martina DvořáčkováJiří Fajkus
May 10, 2016·Nucleus·Agnieszka DobrzynskaPeter Askjaer
May 24, 2016·Cell·Marina FericClifford P Brangwynne
Sep 1, 2016·Methods in Molecular Biology·Frédéric PontvianneJulio Sáez-Vásquez

❮ Previous
Next ❯

Citations

Mar 15, 2019·Nucleus·Ariadna Picart-PicoloFrédéric Pontvianne
Apr 3, 2020·Journal of Plant Research·Frédéric Pontvianne, Stefan Grob
Jun 20, 2020·Journal of Experimental Botany·Ana Paula SantosSara Farrona
Jul 27, 2018·Histochemistry and Cell Biology·Christian Schöfer, Klara Weipoltshammer

❮ Previous
Next ❯

Methods Mentioned

BETA
transmission electron microscopy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Journal of Cell Science
H GinistyP Bouvet
Cold Spring Harbor Symposia on Quantitative Biology
S A GerbiT S Lange
Trends in Genetics : TIG
Attila Németh, Gernot Längst
Seikagaku. The Journal of Japanese Biochemical Society
Mitsuru Okuwaki
© 2021 Meta ULC. All rights reserved