PMID: 6983328Nov 1, 1982Paper

Plasma 25-hydroxyvitamin D and rickets in infants of extremely low birthweight

Archives of Disease in Childhood
N McIntoshO G Brooke

Abstract

Rickets is now a well-known entity in infants of very low birthweight. In a 1-year period (1981) 8 of 15 neonatal survivors whose birthweight was less than 1000 g (extremely low birthweight) developed rickets despite high supplementation with ergo-calciferol, 2000 units a day. At the time of radiological diagnosis their postnatal age was 8 (range 5-14) weeks, and they all had normal or high plasma concentrations of 25-hydroxyvitamin D (mean 80 nmol/l, range 40-160 nmol/l). Although 4 infants received alfacalcidol which healed the rickets, in 4 infants the rickets healed spontaneously without change in treatment. The results suggest that inadequate vitamin D supplementation is not the cause of rickets in such infants.

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Citations

Jan 1, 1987·Pediatric Radiology·A J LyonJ E Williams
Oct 13, 1984·Lancet·N McIntoshK A Wheeler
Jan 24, 1987·Lancet
Oct 11, 2005·Acta Paediatrica. Supplement·Sergio Demarini
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May 1, 1983·Archives of Disease in Childhood·I KovarP Mayne
Jun 1, 1983·Archives of Disease in Childhood·C McCowen, E Hey
Aug 1, 1983·Archives of Disease in Childhood·O G Brooke
Dec 1, 1984·Archives of Disease in Childhood·A J LyonO G Brooke
Dec 1, 1984·Archives of Disease in Childhood·A J Lyon, N McIntosh
Jul 1, 1985·Archives of Disease in Childhood·O G Brooke, A Lucas
May 1, 1986·Archives of Disease in Childhood·G Aiken, W Lenney
Sep 1, 1986·Archives of Disease in Childhood·J R JamesR Arthur
Jul 1, 1989·Archives of Disease in Childhood·A LucasR Morley
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