Plasma-activated water: a new and effective alternative for duodenoscope reprocessing

Infection and Drug Resistance
Gheorghe G BălanMihai Mareş

Abstract

Duodenoscopes have been widely used for both diagnostic and therapeutic endoscopic retrograde cholangiopancreatography procedures. Numerous outbreaks of duodenoscope-associated infections involving multidrug-resistant bacteria have recently been reported. Plasma activated water (PAW) has been widely considered an effective agent for surface decontamination and is increasingly used for disinfection of medical equipment. The aim of this study was to evaluate whether the duodenoscopes currently on market are suited for the repeated use of PAW and to test the efficacy of PAW for their disinfection. In order to evaluate the disinfection efficacy and the required time of contact, the duodenoscope samples were contaminated by immersing them in fasted-state simulated intestinal fluid containing Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa, prior to PAW exposure. In order to test the duodenoscope polymer compatibility with PAW, a challenge test was conducted by immersing the samples in PAW for 30 minutes daily for 45 consecutive days. Significant reductions in bacterial populations were achieved after 30 minutes of PAW treatment, indicating a high-level disinfection. Atomic force microscop...Continue Reading

Citations

Jul 31, 2020·Materials·Mariana PintealaRadu D Rusu
Dec 21, 2018·Digestive Diseases and Sciences·M Rubayat RahmanHemant Goyal
Oct 24, 2019·International Journal of Molecular Sciences·Akikazu SakudoTakashi Onodera
Jun 28, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gheorghe G BalanCatalin Victor Sfarti
Dec 19, 2020·Biomedical Instrumentation & Technology·Michael WongK Scott Phillips
Jan 15, 2021·Comprehensive Reviews in Food Science and Food Safety·Samuel HeriantoHsiu-Ling Chen
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Methods Mentioned

BETA
scanning
atomic
X-ray
AFM

Software Mentioned

Gwyddion

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