PMID: 7091024Jul 1, 1982Paper

Plasma amino acid responses in humans to evening meals of differing nutritional composition

The American Journal of Clinical Nutrition
D V AshleyP D Leathwood

Abstract

The effect of a carbohydrate or a 20% protein (HP) or a carbohydrate + 0.4% tryptophan (TRP) evening meal on plasma amino acids and on plasma neutral amino acid (NAA) ratios was studied in eight healthy men. After consumption of the protein meal, plasma amino acids rose after 1 h and remained at the same level at 2 h. The dietary profile of the essential amino acids, except for TRP, was retained in the plasma. The plasma profile of nonessential amino acids was not related to the dietary pattern. Glutamic acid and aspartic acid increased several-fold less and alanine several-fold more than would be expected from their dietary concentrations. The tyrosine/NAA and phenylalanine/NAA ratios were not altered by any of the meals and the TRP/NAA ratio was increased only by the carbohydrate + 0.4% TRP meal. The leucine/NAA and isoleucine/NAA ratios were decreased by the carbohydrate and carbohydrate + TRP and increased by the 20% protein meals, while valine/NAA was decreased by the carbohydrate + TRP and HP but increased by the carbohydrate meal. From these data it is concluded that if brain neurotransmitter synthesis is controlled by the same mechanisms as in rats, then the evening meal containing added TRP was the only one of the meal...Continue Reading

Citations

Feb 1, 1987·The Proceedings of the Nutrition Society·P D Leathwood
Jun 1, 1986·Postgraduate Medicine·E M Grossman
Jan 1, 1985·Journal of Neural Transmission·S E Møller
Jan 1, 1986·Journal of Neural Transmission·H R LiebermanN Finer
Jul 1, 1995·The British Journal of Nutrition·A S WellsA Craig
Feb 10, 2009·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·A A-B BadawyAlex Steptoe
Mar 23, 2009·International Journal of Tryptophan Research : IJTR·Dawn M RichardDonald M Dougherty
Dec 19, 2018·Geriatrics & Gerontology International·Yusuke AdachiKentaro Shimokado
Feb 7, 2001·The American Journal of Clinical Nutrition·F J van SpronsenP G Smit
Feb 21, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·L RodriguezA M Goldstein
Mar 1, 1996·Amino Acids·E L SainioS N Young
Jul 9, 2014·Proceedings of the National Academy of Sciences of the United States of America·Sarah K DaviesDebra J Skene
Aug 7, 2017·International Journal of Legal Medicine·Karolina LechManfred Kayser
Jul 5, 2012·Journal of Internal Medicine·M H E ChristensenE A Lien
Dec 17, 2008·Journal of Psychopharmacology·A A-B Badawy
Oct 9, 2002·The Journal of Nutrition·Hélène FouilletDaniel Tomé
Jan 27, 1999·Analytical Biochemistry·C PapageorgopoulosM K Hellerstein
Jun 20, 1986·Journal of Chromatography·Z DeylM Horakova
Aug 8, 1997·Clinica Chimica Acta; International Journal of Clinical Chemistry·H S BrandL Abraham-Inpijn

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Catecholamines
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