PMID: 2509663Nov 1, 1989Paper

Plasma carnitine concentration and lipid metabolism in infants receiving parenteral nutrition

The Journal of Pediatrics
M L ChristensenM C Storm

Abstract

The relationships among plasma total carnitine concentration, postnatal age, and fatty acid metabolism were evaluated in 57 infants receiving parenteral nutrition. Concentrations of plasma carnitine, triglycerides, free fatty acids, acetoacetate, and beta-hydroxybutyrate were determined before and at 2 and 4 hours from the beginning of a standardized 2-hour lipid infusion. Plasma carnitine concentrations declined with increasing postnatal age. There were no significant differences in gestational age or triglyceride concentrations between infants less than or equal to 4 weeks of age and those greater than 4 weeks of age, whereas free fatty acid concentrations were lower and acetoacetate and beta-hydroxybutyrate concentrations were higher in the younger infants. Infants less than or equal to 4 weeks of age were further grouped according to plasma carnitine concentration greater than 13 nmol/ml (group 1) and less than or equal to 13 nmol/ml (group 2) and were then compared with infants greater than 4 weeks of age (group 3). There were no significant differences in triglyceride concentrations among the three groups; free fatty acids, acetoacetate, and beta-hydroxybutyrate concentrations for group 2 patients were similar to those of...Continue Reading

References

Nov 1, 1979·The American Journal of Clinical Nutrition·P R BorumH P Broquist
Dec 1, 1979·The Journal of Pediatrics·D SchiffP Hahn
Oct 1, 1985·Journal of Pediatric Gastroenterology and Nutrition·Y Y YehP Zee
Mar 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·G Cederblad, S Lindstedt
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Jul 1, 1984·Pediatric Research·J P Shenai, P R Borum
Apr 1, 1962·Klinische Wochenschrift·F H KREUTZ

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Citations

Apr 2, 1999·Early Human Development·J ArenasY Campos
Jul 1, 1995·Journal of Pediatric Surgery·D N LinzM M Ziegler
Jul 1, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Catherine M CrillRichard A Helms
Mar 22, 2007·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Catherine M Crill, Richard A Helms
Jan 16, 2018·EFSA Journal·UNKNOWN EFSA Panel on Dietetic Products, Nutrition and Allergies (EFSA NDA Panel)Alfonso Siani
Apr 1, 1991·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·O J Heinonen, J Takala
Apr 3, 2002·Pediatrics·Jane O'DonnellKeith J Barrington

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