Plasma Chemerin Levels Are Increased in ST Elevation Myocardial Infarction Patients with High Thrombus Burden

Cardiology Research and Practice
Ahmet Hakan AteşSelim Kul

Abstract

To investigate plasma chemerin levels in ST elevation myocardial infarction (STEMI) patients and find out possible relationships between plasma chemerin levels and angiographic characteristics. Ninety-seven consecutive patients who presented with STEMI and underwent primary percutaneous coronary intervention (PCI) with coronary stents were enrolled, and 30 age- and sex-matched patients with stable angina pectoris who underwent coronary angiography formed the control group. Angiographic characteristics of the patients including thrombolysis in myocardial infarction (TIMI) thrombus and Gensini scores were noted. Blood samples were taken to detect several biochemical markers including plasma chemerin levels at the admission to hospital. Serum chemerin and C-reactive protein (CRP) levels were significantly increased in patients with STEMI. Among STEMI patients, serum chemerin levels were significantly higher in patients with high thrombus burden (581.5 ± 173.7 versus 451.3 ± 101.2 mg/dL, p < 0.001). CRP levels and peak creatine kinase-MB (CK-MB) levels were higher, and left ventricular ejection fraction and post-PCI TIMI flow were lower in patients with high thrombus burden. After multivariate analysis, serum chemerin levels were a...Continue Reading

References

Feb 1, 1983·The American Journal of Cardiology·G G Gensini
Jul 1, 1997·The Journal of Investigative Dermatology·S NagpalR A Chandraratna
Aug 23, 2000·The Journal of Clinical Investigation·B B Kahn, J S Flier
Sep 21, 2000·Trends in Endocrinology and Metabolism : TEM·R S Ahima, J S Flier
Apr 6, 2004·Current Opinion in Pharmacology·Samir E AlamKamal F Badr
Oct 8, 2004·The British Journal of Nutrition·Paul Trayhurn, I Stuart Wood
Jun 24, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Valérie WittamerDavid Communi
Nov 16, 2005·Obesity Research·Tobias PischonEberhard Windler
Apr 8, 2006·Physiological Reviews·Alain Tedgui, Ziad Mallat
Jul 20, 2007·The Journal of Biological Chemistry·Kerry B GoralskiChristopher J Sinal
Jun 30, 2009·Clinical Endocrinology·Johanna WeigertChrista Buechler
Feb 11, 2010·Journal of Atherosclerosis and Thrombosis·Sofia G SpiroglouHelen H Papadaki
Jun 18, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·On Topaz
Nov 23, 2011·Journal of Atherosclerosis and Thrombosis·Hye Jin YooSei Hyun Baik
May 23, 2012·Endocrine·Alexandra A RomanChristopher J Sinal
Apr 20, 2016·Therapeutic Advances in Endocrinology and Metabolism·Sinan İnciPınar Doğan
Jun 9, 2016·Anatolian Journal of Cardiology·Kadriye AydınAlper Gürlek

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Citations

Apr 14, 2020·Current Pharmaceutical Design·Konstantinos MourouzisDimitris Tousoulis

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Methods Mentioned

BETA
ELISA

Software Mentioned

Statistical Package for Social Sciences ( SPSS

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