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Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia

Journal of Neurology, Neurosurgery, and Psychiatry

Jan 16, 2020

Carolin HellerGENFI

Abstract

There are few validated fluid biomarkers in frontotemporal dementia (FTD). Glial fibrillary acidic protein (GFAP) is a measure of astrogliosis, a known pathological process of FTD, but has yet to be explored as potential biomarker. Plasma GFAP and neurofilament light chain (NfL) concent...read more

Mentioned in this Paper

C9orf72 gene
Neurofibrillary Mapt (Tau)-positive Tangles
Brain
Mini-mental State Examination
Frontotemporal Lobar Degeneration
Temporal Lobe
GFAP
GRN
Magnetic Resonance Imaging
Plasma
29
1
1
Paper Details
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Related Papers

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Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study

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© 2020 Meta ULC. All rights reserved

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia

Journal of Neurology, Neurosurgery, and Psychiatry

Jan 16, 2020

Carolin HellerGENFI

PMID: 31937580

DOI: 10.1136/jnnp-2019-321954

Abstract

There are few validated fluid biomarkers in frontotemporal dementia (FTD). Glial fibrillary acidic protein (GFAP) is a measure of astrogliosis, a known pathological process of FTD, but has yet to be explored as potential biomarker. Plasma GFAP and neurofilament light chain (NfL) concent...read more

Mentioned in this Paper

C9orf72 gene
Neurofibrillary Mapt (Tau)-positive Tangles
Brain
Mini-mental State Examination
Frontotemporal Lobar Degeneration
Temporal Lobe
GFAP
GRN
Magnetic Resonance Imaging
Plasma
29
1
1

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CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

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Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study

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