PMID: 7545660Jun 1, 1995Paper

Plasma growth hormone, insulin-like growth factor I, and insulin-like growth factor binding proteins in pigs with divergent genetic merit for postweaning average daily gain

Journal of Animal Science
A C ClutterD S Buchanan

Abstract

Characteristics of growth hormone (GH), IGF-I, and IGF-binding proteins (IGFBP) were studied in gilts sampled from lines of pigs selected for either fast (line F, n = 14) or slow (line S, n = 14) postweaning ADG. Repeated blood samples were obtained from gilts (approximately 55 kg BW) during a period of feed deprivation and again during refeeding. Averaged across time, the difference in mean plasma GH concentrations of F and S gilts was not significant (7.7 vs 6.4 ng/mL; P > .20) during feed deprivation, and frequently, height, and amplitude of GH pulses did not differ (P > .25) for F and S pigs. Overall, F gilts had greater concentrations of plasma IGF-I than S gilts during feed deprivation (217.3 vs 145.1 ng/mL; P < .03). Across line, plasma IGF-I decreased (P < .01) during feed deprivation. Average GH did not differ (P > .40) for F and S gilts during the refeeding period. Average plasma IGF-I tended (P = .05) to be greater in F gilts than in S gilts during refeeding. Consistent with changes over time during feed deprivation, plasma IGF-I averaged across line increased (P < .01) in response to refeeding. Averaged across time (0 and 48 h refeeding), activity of IGFBP-2 (singlet band at 34 kDa) did not differ significantly (P =...Continue Reading

Citations

Mar 1, 2014·Animal : an International Journal of Animal Bioscience·M J SlifierzA Farzan
May 27, 2010·American Journal of Physiology. Endocrinology and Metabolism·Charlotte RehfeldtAndreas Hoeflich
Jan 23, 1998·Domestic Animal Endocrinology·A C ClutterD S Buchanan
Oct 12, 2000·Domestic Animal Endocrinology·P Sellier
Mar 30, 2021·Journal of Animal Science·Carola M C Van der Peet-SchweringAlfons J M Jansman
Sep 15, 2000·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·A HoeflichE Wolf
Dec 10, 2013·BMC Veterinary Research·Mackenzie J SlifierzAbdolvahab Farzan

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