PMID: 8608666Nov 1, 1995Paper

Plasma human brain natriuretic peptide in chronic renal failure

Clinical Nephrology
T AkibaF Marumo

Abstract

Brain natriuretic peptide (BNP) is a polypeptide hormone which is homologous with atrial natriuretic peptide (ANP). Since the 2 hormones partially share common secretory regulation we simultaneously assessed plasma BNP and ANP in patients with chronic glomerulonephritis without apparent cardiac involvement. Blood samples were taken from patients with serum creatinine (Cr) 0.5-1.2 mg/dl (normal renal function), patients with Cr > 1.2 mg/dl (chronic renal failure) and dialysis patients. BNP did not correlate with serum Cr, which indicated our antibody did not recognize accumulated metabolites due to decreased renal function. BNP and ANP decreased after dialysis-(p < 0.01). Changes of BNP during HD correlated with changes in body weight (p < 0.05). Plasma BNP concentrations were 12.0 +/- 22.0 pg/ml in patients with normal renal function, 17.6 +/- 23.4 pg/ml in chronic renal failure, and 91.5 +/- 93.5 in dialysis patients (p < 0.05 compared with patients with normal renal function). Plasma BNP/ANP ratios were 0.507 +/- 0.646 in patients with normal renal function, 0.392 +/- 0.842 in chronic renal failure, and 0.573 +/- 0.431 in dialysis patients (p < 0.05, compared with chronic renal failure). Increased ANP in chronic renal failure...Continue Reading

References

Aug 1, 1979·Kidney International·W F Finn, R L Chevalier
Mar 1, 1975·The Journal of Clinical Investigation·R C Blantz
Aug 1, 1975·Antimicrobial Agents and Chemotherapy·W O HarrisonM Turck
Feb 1, 1976·The Journal of Clinical Investigation·R C BlantzB J Tucker
Apr 1, 1976·Proceedings of the Society for Experimental Biology and Medicine·W M BennettG A Porter
Jan 1, 1990·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·H H NeumayerK Wagner
Jan 1, 1987·Journal of Cardiovascular Pharmacology·S M LeeU F Michael
Sep 1, 1987·The Journal of Clinical Investigation·M NakamotoR W Schrier
Nov 1, 1987·The Journal of Clinical Investigation·S G ShawA Paternostro
Sep 1, 1987·Kidney International·R W SchrierT J Burke
Dec 1, 1973·Kidney International·G A TannerS Sophasan
Jul 1, 1974·Proceedings of the Society for Experimental Biology and Medicine·C H HsuJ M Weller
Nov 1, 1972·Circulation Research·W FlamenbaumA J Saladino
Nov 1, 1980·Kidney International·J P MorinJ P Fillastre
Mar 1, 1983·Journal of Cardiovascular Pharmacology·Y AbeK Yamamoto
Nov 1, 1984·Hypertension·R Sivertsson
Feb 1, 1981·Kidney International·N SchorB M Brenner
Mar 1, 1993·Kidney International·N Honda, A Hishida
May 1, 1993·Kidney International·J V Bonventre

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.