PMID: 8610224Jan 1, 1995Paper

Plasma interleukin-7 (IL-7) and IL-8 concentrations in acute rheumatic fever and chronic rheumatic heart disease

Scandinavian Journal of Rheumatology
N Kütükçüler, Nazmi Narin

Abstract

Interleukin-7 (IL-7) and IL-8 productions in 25 children with acute rheumatic fever (ARF) and in 15 children with chronic rheumatic heart disease (CRHD) and in 15 children with streptococcal pharyngitis (SP), were investigated in order to determine whether they have a role in the pathogenesis of rheumatic fever. Significantly higher IL-8 levels were found in ARF patients in the clinically active period. IL-7 concentrations remained unchanged during different stages of rheumatic fever. The decrease of elevated IL-8 concentrations within 3 months and normal IL-8 concentrations in patients with CRHD and SP indicate an excessive production of IL-8, probably by cellular infiltrates in the joint throughout the active period of rheumatic disease.

References

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Citations

Feb 13, 2001·European Journal of Heart Failure·Z GölbaşiD Erbaş
Sep 1, 1997·Pediatric Hematology and Oncology·G Nişli
Oct 30, 2007·Clinical Biochemistry·Sevil KurbanAysel Kiyici
Jun 19, 2013·Pediatric Cardiology·Murat ÇiftelAbdullah Kocabaş
Oct 22, 2003·Annals of Tropical Paediatrics·Ibrahim H YamanKemal Baysal
Nov 19, 2014·Cardiology in the Young·Mustafa ArgunNazmi Narin
Jun 17, 2014·Cardiology in the Young·Huriye OzgenZubeyir Kilic
Sep 12, 2013·Journal of Cardiovascular Disease Research·N Rama KumariL Satya Ramakrishna
Jul 25, 2019·Pediatrics International : Official Journal of the Japan Pediatric Society·Ayfer Gözü PirincciogluFatma Birgul Işik

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