PMID: 5904983Jan 1, 1966

Plasma lactate dehydrogenase in megaloblastic anaemia

Journal of Clinical Pathology
C F McCarthyA E Read


Raised plasma lactate dehydrogenase (LDH) values were found in 26 patients with marked megaloblastic anaemia due either to vitamin B(12) or folic-acid deficiency or a combination of these factors.Minor megaloblastic changes were not usually accompanied by plasma LDH elevation. Serial LDH estimations were as valuable as serial reticulocyte counts in assessing the response to physiological doses of folic acid and therefore in deciding whether megaloblastic anaemia is partially or completely due to folic acid deficiency.


Jan 1, 1978·Irish Journal of Medical Science·F M StevensC F McCarthy
Jul 1, 1984·Cell Biochemistry and Function·A W Skillen
Nov 1, 1992·European Journal of Haematology·R Carmel, B S Skikne
Jan 1, 1990·European Journal of Haematology·A P RabinowitzR Carmel
Sep 1, 1973·CRC Critical Reviews in Clinical Laboratory Sciences·H E SauberlichJ H Skala

Related Concepts

Anemia, Macrocytic
Clinical Enzyme Tests (Procedure)
Folic Acid Deficiency
Lactate Dehydrogenase
Vitamin B 12 Deficiency

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