PMID: 6991646Jun 1, 1980Paper

Plasma levodopa, dopamine and therapeutic response following levodopa therapy of Parkinsonian patients

Journal of the Neurological Sciences
M N RossorC T Dollery

Abstract

In a double blind placebo controlled study of 6 Parkinsonian patients given a single dose of oral levodopa, the plasma levodopa and dopamine as measured by a radioenzymatic method both correlated with clinical improvement. There was a closer correlation with plasma dopamine than with plasma levodopa and it is proposed that peripheral decarboxylation may reflect central decarboxylation.

References

Feb 1, 1977·Journal of Neurology, Neurosurgery, and Psychiatry·A Galea-DebonoJ Walters
Feb 1, 1973·Proceedings of the Society for Experimental Biology and Medicine·T B TjandramagaA H Anton
Jul 1, 1973·Neurology·P S PapavasiliouW H Lawrence
May 1, 1967·Neurology·M M Hoehn, M D Yahr

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Citations

Jan 1, 1989·Journal of Neural Transmission. Parkinson's Disease and Dementia Section·P DostertD Vernay
Oct 18, 2003·Biochemical Pharmacology·Jae Joon LeeMyung Koo Lee
Feb 1, 1990·British Journal of Clinical Pharmacology·J R HughesR J Dobbs
Jun 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·A J Lees
Oct 4, 2005·Journal of Pharmaceutical Sciences·Ayman AllahhamDavid Mainwaring
May 7, 2008·European Journal of Pharmacology·Yoo Jung YangMyung Koo Lee
Jun 1, 1988·Annals of Neurology·R KurlanI Shoulson
Jul 5, 2011·Progress in Neurobiology·Janusz LipskiNicola B Mercuri
Apr 1, 1982·Agents and Actions·P W IndC T Dollery
Apr 19, 1991·Journal of Chromatography·N DizdarB Kågedal

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