PMID: 9174470Jun 1, 1997Paper

Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis

The American Journal of Clinical Nutrition
W H HowellJ A Gaines

Abstract

Quantitative relations between dietary fat and cholesterol and plasma lipid concentrations have been the subject of much study and some controversy during the past 40 y. Previous meta-analyses have focused on the most tightly controlled, highest-quality experiments. To test whether the findings of these investigations are generalizable to broader experimental settings and to the design of practical dietary education interventions, data from 224 published studies on 8143 subjects in 366 independent groups including 878 diet-blood lipid comparisons were subjected to weighted multiple-regression analysis. Inclusion criteria specified intervention studies published in English between 1966 and 1994 reporting quantitative data on changes in dietary cholesterol and fat and corresponding changes in serum cholesterol, triacylglycerol, and lipoprotein cholesterol concentrations. Regression models are reported for serum total cholesterol, triacylglycerol, and low-density-high-density-, and very-low-density-lipoprotein cholesterol, with multiple correlations of 0.74, 0.65, 0.41, 0.14, and 0.34, respectively. Interactions of dietary factors, initial dietary intakes and serum concentrations, and study and subject characteristics had little e...Continue Reading

Citations

Apr 14, 2000·Journal of the American College of Nutrition·Z R Cordero-MacIntyreM L Fernandez
Jul 27, 2001·The American Journal of Clinical Nutrition·J W StewartD C Beitz
Jan 30, 2002·The American Journal of Clinical Nutrition·Donald J McNamara
Oct 3, 2002·Journal of the American College of Nutrition·Marian L NeuhouserLawrence J Cheskin
Sep 25, 2002·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·F RobinsonG Stratton
Jun 21, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Robert H KnoppSteven E Kahn
Dec 13, 2005·Current Opinion in Clinical Nutrition and Metabolic Care·Maria Luz Fernandez
Aug 6, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J S Vander WalN V Dhurandhar
Aug 22, 2009·Journal of Advanced Nursing·Paula M BrauerJulie Horrocks
Oct 27, 2009·Current Atherosclerosis Reports·Luc Djoussé, J Michael Gaziano
Jul 18, 2009·Public Health Nutrition·Nga Tran, Leila Barraj
Jul 17, 2010·Public Health Nutrition·Carolyn G ScraffordPamela J Mink
Mar 5, 2014·Alcoholism, Clinical and Experimental Research·Anna BukiyaAlexander Fedinec
Jan 10, 2019·Lipids in Health and Disease·Shuo YangQing-Hui Zhang
Sep 24, 2019·Journal of the International Neuropsychological Society : JINS·Melissa LamarMartha L Daviglus
Oct 7, 2000·Journal of the American College of Nutrition·D J McNamara
Jun 13, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alina GavrilaChristos S Mantzoros
Nov 13, 2002·European Journal of Clinical Nutrition·H M KarvonenE S Sarkkinen
Aug 30, 2000·Journal of the American College of Nutrition·A DuringB Entressangles
Apr 15, 2006·The Journal of Nutrition·Kristin L HerronMaria Luz Fernandez
Oct 28, 2004·Biochemical Society Transactions·J Shepherd
May 26, 2004·The American Journal of Clinical Nutrition·Mihaela TanasescuFrank B Hu
Apr 11, 2008·The American Journal of Clinical Nutrition·Luc Djoussé, J Michael Gaziano
Nov 16, 2006·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·A MeadUNKNOWN Thoracic Dietitians Interest Group (Specialist group of the British Dietetic Association)
Oct 22, 2008·Pediatrics International : Official Journal of the Japan Pediatric Society·Uruwan YamborisutWanphen Wimonpeerapattana
Nov 1, 2011·Current Opinion in Clinical Nutrition and Metabolic Care·Maria L Fernandez
Aug 5, 2010·Current Atherosclerosis Reports·Maria Luz Fernandez, Mariana Calle
Oct 28, 2015·Nutrients·Donald J McNamara
Jun 26, 2015·The American Journal of Clinical Nutrition·Samantha BergerElizabeth J Johnson
Oct 7, 2016·Journal of the American College of Nutrition·Dominik D AlexanderSarah S Cohen
Jul 22, 1998·Arteriosclerosis, Thrombosis, and Vascular Biology·D L RainwaterJ L Vandeberg
Apr 11, 2001·Journal of the American College of Nutrition·F B HuW C Willett
Oct 7, 2000·Journal of the American College of Nutrition·J W AndersonD J Jenkins

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