PMID: 9649598Jul 3, 1998Paper

Plasma lipid response to hypolipidemic diets in young healthy non-obese men varies with body mass index

The Journal of Nutrition
S JansenFrancisco Pérez-Jiménez

Abstract

Lipid response to dietary fat is highly variable among individuals of a population. The aim of this study was to establish whether being overweight is one of the factors that determines this response. Forty-one non-obese healthy men were divided into two groups according to body mass index as follows: controls, <25 kg/m2; overweight, >25 kg/m2 but <30 kg/m2. After consuming a saturated fat-rich diet (SAT diet: 38% fat, 20% saturated) for 4 wk, subjects were switched to a low fat diet [National Cholesterol Education Program (NCEP)-I diet: 28% fat, 10% saturated] for 4 wk and then to a monounsaturated fat-rich diet (MUFA diet: 38% fat, 22% monounsaturated) for 4 wk. Data were analyzed by Student's t test and two-way ANOVA for repeated measures. After consuming the NCEP-I diet, the overweight subjects had a smaller decrease relative to the SAT diet period in plasma total cholesterol [-0.30 vs. -0.67 mmol/L (-7 vs. -16%), P < 0.02] and low density lipoprotein-cholesterol concentrations [-0.24 vs. -0.55 mmol/L (-9 vs. -21%), P < 0.04] than controls. However, in the overweight subjects, the MUFA diet produced a greater decrease in plasma triglycerides than in the controls relative to the SAT diet period [-0.36 vs. -0.03 mmol/L (-26 v...Continue Reading

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Citations

Sep 15, 2015·Journal of Korean Academy of Nursing·Guna LeeSook Ja Yang
Oct 25, 2006·Current Cardiology Reports·Martijn B Katan
Nov 11, 2005·The American Journal of Clinical Nutrition·Jose M Ordovas
Apr 5, 2001·Current Atherosclerosis Reports·J M Ordovas
Jun 24, 2006·Arteriosclerosis, Thrombosis, and Vascular Biology·Amy E GrielPenny M Kris-Etherton
Feb 15, 2012·Advances in Nutrition·Michael R FlockPenny M Kris-Etherton
Jun 20, 2019·The American Journal of Clinical Nutrition·Tine Mejlbo SundførSerena Tonstad
Feb 3, 2007·European Journal of Clinical Nutrition·H LindqvistA S Sandberg
Apr 17, 2008·European Journal of Nutrition·Milan NikolicVesna Niketic
Jul 1, 2010·Nutrients·Emilio Ros
Jun 21, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Robert H KnoppSteven E Kahn
Nov 1, 2005·Current Atherosclerosis Reports·Martijn B Katan
Jan 22, 2010·The American Journal of Clinical Nutrition·Patty W Siri-TarinoRonald M Krauss

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