Abstract
Lipid response to dietary fat is highly variable among individuals of a population. The aim of this study was to establish whether being overweight is one of the factors that determines this response. Forty-one non-obese healthy men were divided into two groups according to body mass index as follows: controls, <25 kg/m2; overweight, >25 kg/m2 but <30 kg/m2. After consuming a saturated fat-rich diet (SAT diet: 38% fat, 20% saturated) for 4 wk, subjects were switched to a low fat diet [National Cholesterol Education Program (NCEP)-I diet: 28% fat, 10% saturated] for 4 wk and then to a monounsaturated fat-rich diet (MUFA diet: 38% fat, 22% monounsaturated) for 4 wk. Data were analyzed by Student's t test and two-way ANOVA for repeated measures. After consuming the NCEP-I diet, the overweight subjects had a smaller decrease relative to the SAT diet period in plasma total cholesterol [-0.30 vs. -0.67 mmol/L (-7 vs. -16%), P < 0.02] and low density lipoprotein-cholesterol concentrations [-0.24 vs. -0.55 mmol/L (-9 vs. -21%), P < 0.04] than controls. However, in the overweight subjects, the MUFA diet produced a greater decrease in plasma triglycerides than in the controls relative to the SAT diet period [-0.36 vs. -0.03 mmol/L (-26 v...Continue Reading
References
Aug 1, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·P M Clifton, P J Nestel
Feb 1, 1992·The American Journal of Clinical Nutrition·T G ColeS Kamath
Jan 1, 1991·American Journal of Epidemiology·L V Van HornB Caan
Jul 1, 1990·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·J P DesprésC Bouchard
Jan 1, 1989·The Medical Clinics of North America·G A Bray
Aug 1, 1985·The Journal of Clinical Investigation·G EgusaB V Howard
Jul 1, 1981·Preventive Medicine·A W CaggiulaG Widdowson
Nov 1, 1982·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·D J GordonF A Franklin
Aug 1, 1995·The American Journal of Clinical Nutrition·M A Denke
May 21, 1994·Lancet·J Lopez-MirandaF Perez-Jimenez
Dec 22, 1993·Journal of Chromatography·V Ruíz-GutiérrezF Pérez-Jiménez
Jan 1, 1993·Annals of Nutrition & Metabolism·M CobbH Teitelbaum
Jan 15, 1993·American Journal of Epidemiology·D C GoffJ Stamler
Aug 1, 1997·Arteriosclerosis, Thrombosis, and Vascular Biology·S JansenF Perez-Jimenez
Jul 1, 1965·Metabolism: Clinical and Experimental·Ancel KeysFrancisco Grande
Citations
Oct 3, 2002·Journal of the American College of Nutrition·Daniel D GallaherJohn Wise
Sep 15, 2015·Journal of Korean Academy of Nursing·Guna LeeSook Ja Yang
Oct 25, 2006·Current Cardiology Reports·Martijn B Katan
Nov 11, 2005·The American Journal of Clinical Nutrition·Michael LefevreMarlene M Most
Nov 11, 2005·The American Journal of Clinical Nutrition·Jose M Ordovas
Oct 22, 2014·The Journal of Nutrition·Sally ChiuRonald M Krauss
Jan 5, 2002·The American Journal of Clinical Nutrition·Jose M OrdovasKatherine Tucker
Apr 5, 2001·Current Atherosclerosis Reports·J M Ordovas
Apr 19, 2007·European Journal of Clinical Nutrition·F FuentesF Pérez-Jiménez
Jun 24, 2006·Arteriosclerosis, Thrombosis, and Vascular Biology·Amy E GrielPenny M Kris-Etherton
Feb 15, 2012·Advances in Nutrition·Michael R FlockPenny M Kris-Etherton
Mar 5, 2016·Journal of the American College of Nutrition·Anna Zasowska-NowakDariusz Nowak
Jun 20, 2019·The American Journal of Clinical Nutrition·Tine Mejlbo SundførSerena Tonstad
Feb 3, 2007·European Journal of Clinical Nutrition·H LindqvistA S Sandberg
Apr 17, 2008·European Journal of Nutrition·Milan NikolicVesna Niketic
Jul 1, 2010·Nutrients·Emilio Ros
May 9, 2012·PloS One·Heidi J SilverRussell A Wilke
Jul 18, 2015·Annual Review of Nutrition·Patty W Siri-TarinoRonald M Krauss
Jun 21, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Robert H KnoppSteven E Kahn
Nov 1, 2005·Current Atherosclerosis Reports·Martijn B Katan
Jan 22, 2010·The American Journal of Clinical Nutrition·Patty W Siri-TarinoRonald M Krauss
Nov 4, 2000·Atherosclerosis·F KeeA E Evans
Nov 19, 2003·Metabolism: Clinical and Experimental·Patrick CoutureNathalie Bergeron
Jul 11, 2006·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Wendy A E AitkenSheila M Williams
Feb 1, 2009·Journal of Clinical Lipidology·Yumei CaoPenny M Kris-Etherton