Plasma lipids and lipoproteins pattern in beta-thalassemia major

Acta Haematologica
M MaioliG M Cherchi


We studied serum lipids and lipoproteins in 20 patients with beta-thalassemia major, under high transfusion programme and regular chelation therapy, and in 20 control subjects. Total cholesterol, HDL-cholesterol, HDL2-and HDL3-cholesterol, apolipoprotein A and B levels were significantly lower in patients with Cooley's anemia, whereas free cholesterol, triglycerides and the HDL-/HDL3-cholesterol ratio did not differ in the two groups. We think that liver damage plays an important role in determining the altered lipoprotein pattern in beta-thalassemia major. However, other factors may contribute to cause such lipid changes.


Feb 6, 2004·BioFactors·D R LaksmitawatiH J Freisleben
Oct 9, 2007·Journal of Pediatric Hematology/oncology·Zuhal Yetkin AyDuran Canatan
Nov 1, 1991·British Journal of Haematology·A W GoldfarbS Eisenberg
May 1, 1993·British Journal of Haematology·D Del PrincipeG Papa
Mar 15, 2003·Clinical Chemistry and Laboratory Medicine : CCLM·Patrizia BrizziSalvatore Musumeci
May 10, 2006·Clinical Chemistry and Laboratory Medicine : CCLM·Rataya LuechapudipornUdom Chantharaksri
Jan 1, 1990·Annals of the New York Academy of Sciences·C VulloA Di Palma
May 4, 2007·International Journal of Laboratory Hematology·G AmendolaR Di Concilio
Feb 1, 1989·Atherosclerosis·M MaioliM G Tidore
Apr 3, 2015·BioMed Research International·Adlette InatiHussein A Abbas
Dec 1, 1996·Annals of Tropical Paediatrics·S GomberC L Abdul Rahiman
Oct 10, 2006·Biochemical and Biophysical Research Communications·Noppawan Phumala MoralesUdom Chantharaksri

❮ Previous
Next ❯

Related Concepts

Related Feeds


Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.