Plasma lipoprotein(A) levels: a comparison between diabetic and non-diabetic patients with acute ischemic stroke

Arquivos de neuro-psiquiatria
Maurus Marques de Almeida HolandaJosé Alberto Gonçalves da Silva

Abstract

The aim of this study was to evaluate lipoprotein(a) (Lp(a)), total cholesterol, high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL), very low density lipoprotein cholesterol (VLDL ), triglycerides, apolipoprotein A (apo A) and B100 (apo B100), uric acid, glycaemic and insulin plasmatic concentrations in patients affected by acute stroke. In this group of patients, we have compared the variables between type 2 diabetic patients and non-diabetic patients. We evaluate a total of 34 non-diabetic patients (22 males and 12 females; mean age 66.71 +/- 10.83 years) and a group of 26 type 2 diabetic patients (15 males and 11 females; mean age 66.35 +/- 9.92 years) in a cross-sectional study. Mean Lp(a) concentration did not significantly differ between type 2 diabetic patients and non-diabetic subjects (29.49 +/- 23.09 vs 44.81 +/- 44.34 mg/dl). The distribution of Lp(a)levels was highly skewed towards the higher levels in both groups, being over 30 mg/dl in 50%. Lp(a) concentration was positively correlated with abdominal adiposity, using waist-hip ratio(WHR)(p< 0.05). No association was found between Lp(a) and others risk factors like sex, age, other lipidic parameters and the presence of stroke. Our...Continue Reading

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Citations

Apr 20, 2006·Arquivos de neuro-psiquiatria·Maurus Marques de Almeida HolandaJosé Alberto Gonçalves da Silva

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